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  • Electronic Resource  (12)
  • 1970-1974  (11)
  • 1955-1959  (1)
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  • Electronic Resource  (12)
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  • 1
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Nachweis, dass derβ-Blocker LB46 am blutperfundierten Papillarmuskel des Hundes eine grössere Aktivität aufweist als 6 andere bekannteβ-Blocker.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature 184 (1959), S. 1418-1418 
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The present communication deals with crystallization and several properties of the two components. Haemolyzate from chum salmon blood saturated with carbon monoxide, was 0-35 saturated with ammonium sulphate at neutral pH and suctioned. The nitrate was 0-6 saturated with the salt and the resulting ...
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Clinical and experimental pharmacology and physiology 1 (1974), S. 0 
    ISSN: 1440-1681
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: SUMMARY 1. Pancreatic secretion has been monitored in the isolated, blood-perfused canine pancreas, and the effects of depletion of serum calcium by infusion of EGTA on the increases in secretion produced by intra-arterial injections of dopamine and secretin have been investigated.2. Under resting conditions in preparations in dogs fasted for 24 h, the mean rate of pancreatic secretion was 16.4 μ1/min (s. e. m. = 2, n= 12). The mean concentrations of protein, bicarbonate and chloride in the pancreatic juice were 53.8 mg/ml (s. e. m. = 4.5), 18.0 mmol/1 (s. e. m. = 1.1) and 122.5 mmol/1 (s. e. m. = 7.5), respectively. Infusion of EGTA had no effect on resting secretion.3. Secretion elicited by dopamine or secretin was diminished about 50% during the intra-arterial infusion of EGTA (10−2 mM/ml) in the perfusing blood. The protein concentration in the secretion was diminished to a similar extent. The concentrations of bicarbonate and chloride in the pancreatic juice was not modified by EGTA infusion.4. Concomitant infusion of an equimolar concentration of CaCl2 solution abolished the inhibitory effects of EGTA infusion on the secretory responses to dopamine or secretin.5. The results suggest that dopamine and secretin influence the exocrine secretions of the pancreas by actions on both acinar and ductular cells. Acinar cell secretion is more susceptible to depletion of serum calcium levels than is secretion from ductular cells.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 28 (1971), S. 1-11 
    ISSN: 1432-1246
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Neurological and electrophysiological examination of 15 workers handling acrylamide in a factory revealed abnormal signs of peripheral nerve functions in all cases. Neurological abnormalities were: absent deep reflexes, decreased superficial sense and suppressed vibration sense. Action potentials in median nerve and tibial nerve were greatly reduced while conduction velocity was not greatly affected. Long-experienced workers had various complaints with ataxic gait and showed abnormal EEG.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    International archives of occupational and environmental health 29 (1972), S. 189-200 
    ISSN: 1432-1246
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary A series of exposure experiments with Triethylaluminum were undertaken using animals, and the following results were obtained: 1. Gas Chromatographic analysis of the exposure gas showed that the gas contained various combustion products of TEA in the air and contained an unidentified substance which had a retention time equivalent to a 6-carbon compound. The substance was assumed to be TEA itself. 2. A moderate systemic effect of “TEA” gas on various organs was observed when it contained considerable amounts of the 6-carbon compound. 3. Characteristic changes in the lungs of animals exposed to “TEA” were found by histological examination. The changes in the lungs were a result of moderate irritation. 4. The effects of exposure to the “TEA-toluene” mixture were more severe in the animals than the effects of “TEA”. Those effects would be mainly due to toluene because the same effects could be seen by the exposure to toluene alone. 5. Direct action of “TEA” on the skin was identical to that of a burn. A possible relation between these results and the clinical symptoms found among some of the workers handling TEA was briefly discussed.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Es wurde die Potenz sechs β-adrenergischer Blockierungsmittel auf positiv inotrope Wirkung von Noradrenalin am isolierten, Blut zuführenden Papillarmuskel des Hundes vergleichend untersucht. Die Reihenfolge der Wirksamkeit: Köl366〉pindolol〉C-3〉Y-6124=YB−2 = propranolol (30:10:5:1)
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Cellular and molecular life sciences 29 (1973), S. 319-320 
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Die Wirksamkeit von Prostaglandin F2α (PGF2α) auf die exokrine Pankreassekretion wurde an einem mit Blut perfundiereten Pankreas-Präparat des Hundes untersucht. PGF2α (100 μg) hemmte die durch Sekretin stimuliete, aber nicht die durch Dopamin stimulierte Sekretion.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Mit neu ausgebauter Methode sind 8 ältere und neuere β-Blocker auf ihre Eigenwirkung und ihre Wirksamkeit als Noradrenalin-Antagonisten geprüft worden. Die abgestuften Wirksamkeitszahlen sind: Kö1366 (20)〉Pindolol (10)〉C-3 (5)〉YB-2=Y-6124 (3)〉Propranolol (1)〉Practolol (2/3)〉Sotalol (1/3).
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Archives of dermatological research 240 (1971), S. 349-364 
    ISSN: 1432-069X
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Zusammenfassung Kleine protoplasmatische Körnchen, welche in verschiedenen verhornenden Epithelien gefunden worden sind und als der Zellmembran aufliegende Körnchen oder Keratinosome bezeichnet wurden, konnten durch Phospholipase C gespalten werden. Körnchen, die in die intercellulären Zwischenräume abgestoßen waren, waren gleichfalls durch Phospholipase C spaltbar. Da angenommen wird, daß Phosphatide einen Teil der intercellularen Kittsubstanz bilden, nicht nur in der Haut, sondern auch in anderen eng zusammengefügten Epithelien, wird die Bezeichnung „Kittkörnchen“ oder „Kittkörper“ für diese Körnchen vorgeschlagen.
    Notes: Summary Small cytoplasmic granules, which have been found in various keratinizing epithelia and called the membrane-coating granules or keratinosomes, were found to be amenable to phospholipase C digestion. Granules discharged into the intercellular spaces could also be digested with phospholipase C. Since it is believed that phospholipids are part of the intercellular cement not only in the skin but in other tightly junctioned epithelia, the name “cement granule” or “cementsome” was proposed for these granules.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1420-9071
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Medicine
    Notes: Zusammenfassung Der Effekt von sechsβ-adrenergischen Blockierungsmitteln auf Akonitin-Arrhythmia bzw. Ouabain-Arrhythmia wurde mittels i.v. Verabreichung vergleichend untersucht. Reihenfolge der Wirksamkeit auf Akonitin-Arrhythmia: Propranolol〉MJ 1999〉LB 46〉H 56/28, ICI 50172 und DCI, und dieselbe auf Ouabain-Arrhythmia: Propranolol, LB 46 und H 56/28 gleichwertig, MJ 1999 und ICI 50172 wirkungslos.
    Type of Medium: Electronic Resource
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