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  • 1
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 71 (1997), S. 2904-2906 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Nd-doped LiNbO3 films have been prepared on (012) sapphire substrates by pulsed laser deposition. LiNbO3 phase is formed using Li rich targets, a 1.5×10−2 mbar oxygen pressure atmosphere, and heating the substrate to 520 °C. The crystallinity of 1-μm-thick films has been enhanced by postdeposition thermal treatments at 600 °C. The [Nd]/[Nb] concentration ratio in the film is equal to its value in the target; however, a limit for the Nd incorporation to the LiNbO3 phase has been found due to the preferential nucleation of Li deficient phases for [Nd]/[Nb]〉0.1. The Nd photoluminescence of the films have been studied at 77 K exciting the 4F3/2 multiplet. The photoluminescence of congruent LiNbO3 single crystals is well reproduced in films prepared from targets with a [Li]/[Nb]=1.6 composition. Films prepared from targets with a [Li]/[Nb]=3 composition, additionally show an emission, with a main maximum at 1064 nm, the splitting of the 4F3/2 multiplet being 80 cm−1. The possible origin of the latter photoluminescence is discussed. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Woodbury, NY : American Institute of Physics (AIP)
    Applied Physics Letters 71 (1997), S. 3382-3384 
    ISSN: 1077-3118
    Source: AIP Digital Archive
    Topics: Physics
    Notes: An ensemble Monte Carlo (EMC) simulator has been used to study bipolar transport in silicon p+n and pn+ homojunctions under forward-bias conditions, both in low- and high-injection regimes. The study focuses on a microscopic analysis of voltage fluctuations in such devices. The method of voltage-noise operation mode provides spatial analysis of the spectral density of voltage fluctuations under constant-current conditions. In the low-frequency range, the presence of shot, thermal, and excess noise due to hot carriers was found when the bias conditions were modified. Also, the EMC method permits ready evaluation of the noise equivalent temperature in both structures from the observed voltage fluctuations. © 1997 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Journal of the American Water Resources Association 33 (1997), S. 0 
    ISSN: 1752-1688
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Architecture, Civil Engineering, Surveying , Geography
    Notes: : A downspout diversion program in an urban area is evaluated to assess the impacts on sanitary sewer flow volumes and cost effectiveness. Sanitary sewer flows and wastewater treatment cost data are compared for the five years before and 1.25 years after the downspout diversion was completed. In order to establish a cause and effect relationship between flow volumes and downspout diversion, measurements of precipitation, consumption patterns, and system loss (maintenance, fire flows, main ruptures) for the before and after time periods were obtained. The results indicate the downspout diversion contributed to a reduction of over 25 percent in the mean flow volumes within the sanitary sewer collection network during all rainfall events, with flow reductions ranging from 25 percent to 62 percent for rainfall depths between 6 mm (0.25 inches) and 25.4 mm (1.0 inches). Costs incurred for wastewater treatment were also reduced significantly, as overtime for overflow maintenance was eliminated. Downspout diversion is a viable nonstructural alternative for sthrmwater flow reduction in highly urbanized communities which may lack available space for large scale detention facilities.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1365-2516
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Visceral leishmaniasis (VL), an endemic parasitosis in Spain, is increasing as an important opportunistic infection in AIDS patients. We describe four cases of severe haemophilic patients with end-stage HIV disease who present with visceral leishmaniasis. We report the clinical course, methods of diagnosis and response to therapy. From the assessed clinical data it does not appear to be any difference with regard to VL either in other HIV risk groups or in immunocompetent groups. In contrast with previous reports, we have found that despite their immunodepressed state, positive serology for Leishmania was found in three of the four cases. A similar observation has been made in patients with VL who are immunodepressed because of other reasons. We also confirm previous reports of poor response and intolerance of antimony treatment, the deteriorating course of the disease in AIDS patients and that there is only a slight relationship between the disease and the cause of patient death. We agree with the proposition that this pathology ought to be included in the definition critera for AIDS.
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Oxford, U.K. and Cambridge, USA : Blackwell Science Ltd
    Scandinavian journal of immunology 45 (1997), S. 0 
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: RadLV-Rs infection induces a murine immunodeficiency syndrome associated with a dramatic enlargement of spleen and lymph nodes. Surprisingly, the lymphoproliferation excludes thymus and Peyer's patches (PP). To understand the cellular interactions underlying lymphoproliferation further, the authors investigated the fate of PP in RadLV-Rs infected mice. The atrophy of PP was mostly due to the depletion of B cells, while the proportion of CD4+ and CD8+ T cells was increased. Nevertheless, B cell phenotype was modified with the emergence of lymphocytes with a low expression of B220 in infected PP. T cells characterized by a memory/activated phenotype in control PP did not undergo phenotypical changes after viral infection (i.e. regarding Thy-1 and CD44 expression). Despite the absence of lymphoproliferation, PP T and B cells displayed altered responses to mitogens in vitro. Finally, alterations of the expression of adhesion molecules and vascular addressins could not explain the atrophy of PP by a reduced homing to this lymphoid site. B cells and T cells from normal PP are clearly different from lymph nodes (LN) lymphocytes. The authors propose that the particular functional state which characterizes PP lymphocytes influences the B cell/T cell crosstalk necessary for RadLV-Rs-induced lymphoproliferation.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [s.l.] : Nature Publishing Group
    Nature genetics 15 (1997), S. 201-204 
    ISSN: 1546-1718
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Medicine
    Notes: [Auszug] Several strains of mice have been created which have reproductive defects secondary to disruption of the hypothalamic-pituitary-gonadal axis3,4. Although these mouse models are useful for studying reproductive function, many of these mice have multiple defects. For example, targeted disruption of ...
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    Allergy 52 (1997), S. 0 
    ISSN: 1398-9995
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1476-4687
    Source: Nature Archives 1869 - 2009
    Topics: Biology , Chemistry and Pharmacology , Medicine , Natural Sciences in General , Physics
    Notes: [Auszug] The cerebellum is essential for fine motor control of movement and posture, and its dysfunction disrupts balance and impairs control of speech, limb and eye movements. The developing cerebellum consists mainly of three types of neuronal cells: granule cells in the external germinal layer, ...
    Type of Medium: Electronic Resource
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  • 9
    ISSN: 1432-069X
    Keywords: Key wordsHsKin17 ; MmKin17 ; Human keratinocytes ; Reconstructed skin ; Differentiation ; Laser cytometer
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract In eukaryotic cells, various proteins homologous to the E. coli RecA protein are involved in the elimination of DNA damage. These proteins contribute to the repair of double-strand breaks and to genetic recombination. The mouse Kin17 protein is recognised by antibodies directed against the RecA protein. Kin17 has a zinc-finger domain allowing binding to curved DNA stretching over illegitimate recombination junctions. In the present study, we identified the human counterpart of the mouse Kin17 protein (named Hs Kin17) in skin cells. We employed an in vitro reconstructed skin model composed of an epidermal sheath lying on a dermal matrix with human fibroblasts embedded in rat collagen type I. The maturation programme (proliferation versus differentiation) of keratinocytes was highly dependent on stromal cells. Immunohistochemical staining of frozen sections obtained from skin specimens was monitored by an interactive laser cytometer. In this way we analysed protein levels in both dermal and epidermal compartments. After having characterised the epithelium, we focused our attention on Hs Kin17 expression. We detected Hs Kin17 in human keratinocytes. Hs Kin17 protein levels increased in proliferating epithelial keratinocytes after 7 days of culture. After 2 weeks of culture, epidermal sheaths acquired most of the differentiated features of mature epithelium. At this time, Hs Kin17 protein dropped below measurable levels in the stratum corneum, and diminished in nucleated cells. This study showed that Hs Kin17 is expressed in human reconstructed epithelium under conditions of hyperproliferation.
    Type of Medium: Electronic Resource
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  • 10
    ISSN: 1432-1130
    Source: Springer Online Journal Archives 1860-2000
    Topics: Chemistry and Pharmacology
    Notes: Abstract The demand for trace element analysis in many fields of application has significantly increased in the last few years. Accuracy is fundamental to analysis and the importance of accurate measurements is widely accepted. Yet most instrumental analytical methods are relative methods and accuracy is established by using certified reference materials for method validation and calibration or by use of a definitive method as isotope dilution analysis (IDA). In this work a new high-resolution ICP mass spectrometer Finnigan MAT “ELEMENT”, which provides mass spectral resolution of 300 up to 7500 and thus eliminates most of the spectral interferences quadrupol mass analyzers are suffering from, is applied in combination with IDA to evaluate the capabilities of these techniques to the accurate determination of element traces in processing chemicals for semiconductor production.
    Type of Medium: Electronic Resource
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