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  • 1
    Digitale Medien
    Digitale Medien
    Preparation, hydrolysis, and oral absorption of lactonyl esters of penicillins (1976)
    s.l. : American Chemical Society
    Journal of medicinal chemistry 19 (1976), S. 1385-1391 
    Details
    ISSN: 1520-4804
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1021/jm00234a007
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  • 2
    Digitale Medien
    Digitale Medien
    Preparation, hydrolysis, and oral absorption of .alpha.-carboxy esters of carbenicillin (1975)
    s.l. : American Chemical Society
    Journal of medicinal chemistry 18 (1975), S. 172-177 
    Details
    ISSN: 1520-4804
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1021/jm00236a013
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  • 3
    Digitale Medien
    Digitale Medien
    Detection of iodine-129 by laser-induced fluorescence spectrometry (1981)
    s.l. : American Chemical Society
    Analytical chemistry 53 (1981), S. 776-778 
    Details
    ISSN: 1520-6882
    Quelle: ACS Legacy Archives
    Thema: Chemie und Pharmazie
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1021/ac00229a007
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  • 4
    Digitale Medien
    Digitale Medien
    Business transformation through outsourcing (2002)
    Bradford : Emerald
    Strategy & leadership 30 (2002), S. 23-28 
    Details
    ISSN: 1087-8572
    Quelle: Emerald Fulltext Archive Database 1994-2005
    Thema: Wirtschaftswissenschaften
    Notizen: Outsourcing is rapidly evolving beyond the simple reengineering of support processes. For many companies, outsourcing partnerships are being used to achieve rapid, sustainable improvement in enterprise-level performance. More specifically, in addition to the baseline value of reducing costs and offloading unimportant activities, partnership with an outsourcing vendor can be used to gain access to competitive skills, improve service levels, and increase the company's ability to respond to changing business needs. To classify an outsourcing program as truly "business transformation", it must change the way the client company works by using outsourcing to achieve a rapid, sustainable radical improvement in performance - as measured by dramatic growth, market repositioning or rapid diversification. The resulting performance improvement can be measured in dramatic gains in share price, market position and return on capital. In short, it is a comprehensive approach that seeks to create new capabilities and then use them to achieve a clear strategic objective. Business transformation outsourcing achieves results by integrating five essential process components: top-level leadership, bold strategic agenda, innovative financial structure, outsourcing to transform critical processes, and focus on enterprise outcomes.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1108/10878570210435342
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  • 5
    Digitale Medien
    Digitale Medien
    Day-Length as a Factor affecting the Variation of Chenopodium spp. in Britain (1960)
    [s.l.] : Nature Publishing Group
    Nature 188 (1960), S. 954-955 
    Details
    ISSN: 1476-4687
    Quelle: Nature Archives 1869 - 2009
    Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik
    Notizen: [Auszug] Previously, Khlebnikova2, Potapenko3, Fuller4 and Wahl5 had shown that many species of the genus Chenopodium were photoperiodically short-day with or without a critical day-length. In addition, Wahl suggested that the day-length factor may be of significance in experimental taxonomy when he showed ...
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1038/188954a0
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  • 6
    Digitale Medien
    Digitale Medien
    A vitalistic model to describe the thermal inactivation ofListeria monocytogenes (1993)
    Springer
    Journal of industrial microbiology and biotechnology 12 (1993), S. 232-239 
    Details
    ISSN: 1476-5535
    Schlagwort(e): Listeria monocytogenes ; Predictive model ; Thermal/heat inactivation ; Death kinetics ; Vitalistic ; Logistic
    Quelle: Springer Online Journal Archives 1860-2000
    Thema: Biologie , Werkstoffwissenschaften, Fertigungsverfahren, Fertigung
    Notizen: Summary Thermal inactivation of microorganisms has traditionally been described as log-linear in nature, that is the reduction in log numbers of survivors decreases in a linear manner with time. This is despite a plethora of data that shows consistent deviations from such kinetics for a wide range of organisms and conditions and that cannot be accounted for by experimental artifacts. Existing thermal death models fail to take such deviations into account and also fail to quantify the effects of heating menstruum on heat sensitivity. The thermal inactivation ofListeria monocytogenes ATCC 19115 has been investigated using a factorially-designed experiment comparing 45 conditions of salt concentration, pH value and temperature. Heating was carried out using a Submerged Coil heating apparatus that minimized experimental artifacts. Low pH values increased, whilst high salt concentrations decreased heat sensitivity. Results showed a significant and consistent deviation from log-linear kinetics, particularly at low temperatures. A number of distributions were tested for suitability to describe the variability of heat sensitivity within the population of heated cells (vitalistic approach). The use of the logistic function and log dose (log time) allowed the development of an accurate unifying predictive model across the whole range of heating conditions. It is proposed that this approach should be tested as a generalized modeling technique for death kinetics of vegetative bacteria.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1007/BF01584195
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  • 7
    Digitale Medien
    Digitale Medien
    Effects of weak acids and external pH on the intracellular pH of Zygosaccharomyces bailii, and its implications in weak-acid resistance (1987)
    New York, NY [u.a.] : Wiley-Blackwell
    Yeast 3 (1987), S. 23-32 
    Details
    ISSN: 0749-503X
    Schlagwort(e): Zygosaccharomyces ; weak-acid resistance ; intracellular pH ; yeast ; Life and Medical Sciences ; Genetics
    Quelle: Wiley InterScience Backfile Collection 1832-2000
    Thema: Biologie
    Notizen: Weak acids and hydrogen ions in different concentration combinations affect the intracellular pH value (pHi) of Zygosaccharomyces bailii. The lowest pHi value measured was not at the most extreme, but at intermediate conditions of inhibition. Proton and organic-acid ejection, on a cell volume basis, is greater in cells grown under inhibitory conditions and is stimulated by weak acids, whilst in cells not grown under inhibitory conditions acid efflux is lower and is depressed by weak acids; this may be important in the maintenance of tolerable pHi values in the presence of weak acids. The concentration of benzoic acid measured internally is identical to the value expected from its pK, external pH and pHi. Addition of fructose to starved cells causes both a decreased pHi and a concomitant efflux of previously loaded benzoic acid, quantitatively in accord with the shift in equilibrium of the freely permeable undissociated acid. There is no evidence that weak acids are actively extruded. Protoplast volume also varies with hydrogen-ion and weak-acid concentration and this too may play a role in intracellular pH maintenace.
    Zusätzliches Material: 3 Ill.
    Materialart: Digitale Medien
    URL: http://dx.doi.org/10.1002/yea.320030105
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