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  • 1
    Electronic Resource
    Electronic Resource
    Interaction of Circular Lining and Interior Linear Crack by Incident SH-Wave (2007)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 348-349 (Sept. 2007), p. 521-524 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In this paper, the method of Green’s function is used to investigate the problem ofdynamic stress concentration of circular lining and interior linear crack impacted by incidentSH-wave. The train of thought for this problem is that: Firstly, a Green’s function is constructed forthe problem, which is a fundamental solution of displacement field for an elastic space possessing acircular lining while bearing out-of-plane harmonic line source force at any point in the lining. Interms of the solution of SH-wave’s scattering by an elastic space with a circular lining, anti-planestresses which are the same in quantity but opposite in direction to those mentioned before, areloaded at the region where the crack existent actually, we called this process “crack-division”.Finally, the expressions of the displacement and stress are given when the lining and the crack existat the same time. Then, by using the expressions, some example is provided to show the effect ofcrack on the dynamic stress concentration around circular lining
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/55/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.348-349.521.pdf
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  • 2
    Electronic Resource
    Electronic Resource
    Dynamic Stress Intensity Problem of SH-Wave by Double Linear Cracks near a Circular Hole (2008)
    s.l. ; Stafa-Zurich, Switzerland
    Key engineering materials Vol. 385-387 (July 2008), p. 105-108 
    Details
    ISSN: 1013-9826
    Source: Scientific.Net: Materials Science & Technology / Trans Tech Publications Archiv 1984-2008
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics
    Notes: In mechanical engineering, circular hole is used widely in structure design. When thestructure is overloaded or the load is changed regularly, cracks emerge and spread. Based on theformer study of dynamic stress concentration problem of SH wave by a crack originating at acircular hole edge, in this paper, the method of Green’s function is used to investigate the problemof dynamic stress intensity problem of double linear cracks near a circular hole impacted byincident SH-wave. The train of thought for this problem is that: Firstly, a Green’s function isconstructed for the problem, which is a fundamental solution of displacement field for an elasticspace possessing a circular hole and a linear crack while bearing out-of-plane harmonic line sourceforce at any point; Secondly, in terms of the solution of SH-wave’s scattering by an elastic spacewith a circular hole and a linear crack, anti-plane stresses which are the same in quantity butopposite in direction to those mentioned before, are loaded at the region where the second crack isin existent actually, we called this process “crack-division”; Finally, the expressions of thedynamic stress intensity factor(DSIF) of the cracks are given when the circular hole and doublelinear crack exist at the same time. Then, by using the expressions, an example was provided toshow the effect of circular hole and cracks on the dynamic stress intensity factor of the cracks
    Type of Medium: Electronic Resource
    URL: http://www.tib-hannover.de/fulltexts/2011/0528/01/57/transtech_doi~10.4028%252Fwww.scientific.net%252FKEM.385-387.105.pdf
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  • 3
    Electronic Resource
    Electronic Resource
    Crystallographic Studies of Isosteric NAD Analogs Bound to Alcohol Dehydrogenase: Specificity and Substrate Binding in Two Ternary Complexes (1994)
    s.l. : American Chemical Society
    Biochemistry 33 (1994), S. 11734-11744 
    Details
    ISSN: 1520-4995
    Source: ACS Legacy Archives
    Topics: Biology , Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/bi00205a009
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  • 4
    Electronic Resource
    Electronic Resource
    Novel type of ion-selective fluorosensor based on the inner filter effect: an optrode for potassium (1993)
    s.l. : American Chemical Society
    Analytical chemistry 65 (1993), S. 123-127 
    Details
    ISSN: 1520-6882
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/ac00050a006
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  • 5
    Electronic Resource
    Electronic Resource
    Effects of environmental factors on the electrooptical properties of conjugated polymers containing oligo(oxyethylene) substituents (1991)
    s.l. : American Chemical Society
    The @journal of physical chemistry 〈Washington, DC〉 95 (1991), S. 8983-8989 
    Details
    Source: ACS Legacy Archives
    Topics: Chemistry and Pharmacology , Physics
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1021/j100175a102
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  • 6
    Electronic Resource
    Electronic Resource
    Relationship between ThMn12 and Th2Ni17 structure types in the YFe11−xTix alloy series (1990)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 67 (1990), S. 4838-4840 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: A series of YFe11−xTix alloys with x=0.10, 0.25, 0.40, 0.50, 0.70, 1.00, 1.25, 1.50, and 2.00 have been investigated using x-ray diffraction, thermomagnetic analysis, the singular point detection technique, and 57Fe Mössbauer spectroscopy. A pure ThMn12 -type phase was observed when 0.7≤x≤1.25. It has Curie temperature of 524 K, anisotropy field of 2.3 T, and average iron magnetic moment of 1.47 μB at room temperature. The relationship between the CaCu5 and the Th2Ni17 or ThMn12 structure types is discussed in terms of substitution of transition-metal dumbbells on Ca sites, and a structural explanation is given for the directions of the iron anisotropy in the 2:17 and 1:12 compounds.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.344753
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  • 7
    Electronic Resource
    Electronic Resource
    Magnetic properties of new ternary R6Ga3Fe11 compounds (1990)
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 67 (1990), S. 4841-4843 
    Details
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: Three new rare earth–iron ternary compounds with the La6Ga3Co11 structure (I4/mcm), Pr6Ga3Fe11, Nd6Ga3Fe11, and Sm6Ga3Fe11, are found to be ferromagnetic with Curie temperatures of 320, 397, and 462 K, respectively. Large anisotropies have been observed from the magnetization curves and the anisotropy field is larger than 7 T at room temperature. First-order magnetization processes were observed for all samples throughout the temperature range of 4.2–300 K. Point charge calculations give A20=1070 K a−20 at the 16l site and −283 K a−20 at the 8f site.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1063/1.344754
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  • 8
    Electronic Resource
    Electronic Resource
    Alcohol Inhibits the Depolarization-Induced Stimulation of Oxidative Phosphorylation in Synaptosomes (1996)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 66 (1996), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: The effects of alcohol and Ca2+ transport inhibitors on depolarization-induced stimulation of oxidative phosphorylation and free-Ca2+ concentrations in rat synaptosomes were investigated. Glucose oxidation was stimulated by depolarization with K+ or veratridine and by the Ca2+ ionophore ionomycin. The stimulation by K+, veratridine, and ionomycin was correlated with elevation of synaptosomal free Ca2+. Depolarization-stimulated respiration was inhibited by verapamil, Cd2+, and ruthenium red but not by diltiazem. Synaptosomal Ca2+ elevation was inhibited by verapamil but not by ruthenium red. These results indicate that the stimulation depends on elevation of mitochondrial free Ca2+. Ethanol, at pharmacological concentrations (50–200 mM), inhibited the Ca2+-dependent stimulation of oxidative phosphorylation. This inhibition resulted, in part, from the inhibition of voltage-gated Ca2+ channels, which inhibited the elevation of synaptosomal free Ca2+, and, in part, from the stimulation of the mitochondrial Ca2+/Na+ antiporter, which inhibited the elevation of the mitochondrial matrix free Ca2+. The inhibition by ethanol of the excitation-induced stimulation of oxidative phosphorylation in the synapse may contribute to the depressant and narcotic effects of alcohol and enhance excitotoxicity.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.1996.66041691.x
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  • 9
    Electronic Resource
    Electronic Resource
    Positronium Annihilation Study of Porosity in Silica Xerogels Prepared by a Sol–Gel Process (2003)
    Westerville, Ohio : American Ceramics Society
    Journal of the American Ceramic Society 86 (2003), S. 0 
    Details
    ISSN: 1551-2916
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Mechanical Engineering, Materials Science, Production Engineering, Mining and Metallurgy, Traffic Engineering, Precision Mechanics , Physics
    Notes: Nano- and mesopores of bulk silica xerogels were studied by means of positron annihilation lifetime measurement as well as nitrogen physisorption. Effects of an alkaline catalyst concentration in the sol–gel process on the pore sizes and specific surface area were investigated. The pore size was estimated from the ortho-positronium lifetime. Remarkable structural changes were found around a relative alkaline concentration of 10−4 (a molar ratio of sodium hydroxide to tetramethyl ortho-silicate). Above this particular catalyst concentration, the nanopore radius decreased from 0.45 to 0.35 nm, whereas the mesopore radius increased from 1 to 8 nm. The positron annihilation lifetime technique was effective in the evaluation of the nano- and mesoscopic structural changes of silica xerogel.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1111/j.1151-2916.2003.tb03529.x
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  • 10
    Electronic Resource
    Electronic Resource
    Irreversible Inhibition of Mitochondrial Complex I by 7-(2-Aminoethyl)-3,4-Dihydro-5-Hydroxy-2H-1,4-Benzothiazine-3-Carboxylic Acid (DHBT-1): A Putative Nigral Endotoxin of Relevance to Parkinson's Disease (1997)
    Oxford, UK : Blackwell Science Ltd
    Journal of neurochemistry 69 (1997), S. 0 
    Details
    ISSN: 1471-4159
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Abstract: Based on a number of lines of evidence, we have proposed recently that a very early step in the pathogenesis of idiopathic Parkinson's disease might be elevated translocation of l-cysteine into neuromelanin-pigmented dopaminergic cell bodies in the substantia nigra. In vitro studies suggest that such an influx of l-cysteine would divert the neuromelanin pathway by scavenging dopamine-o-quinone, the proximate autoxidation product of dopamine, to give 5-S-cysteinyldopamine, which is oxidized further to 7-(2-aminoethyl)-3,4-dihydro-5-hydroxy-2H-1,4-benzothiazine-3-carboxylic acid (DHBT-1) and other cysteinyldopamines and dihydrobenzothiazines. In this study, it is demonstrated that DHBT-1 inhibits ADP-stimulated oxidation of malate and pyruvate (state 3 or complex I respiration) when incubated with intact rat brain mitochondria with an IC50 of ∼0.80 mM. Incubation of DHBT-1 with freeze-thawed rat brain mitochondria in both the presence and absence of KCN and/or NADH causes an irreversible, time-dependent decrease of NADH-coenzyme Q1 reductase activity. Significantly lower concentrations of DHBT-1 are necessary to cause this effect when mitochondrial membranes are incubated in the absence of KCN and NADH. The irreversible inhibition of mitochondrial complex I caused by DHBT-1 under the latter conditions could be blocked only partially by glutathione, ascorbic acid, superoxide dismutase, or catalase. Together, these results suggest that DHBT-1 can cross the outer mitochondrial membrane and irreversibly inhibit complex I by a mechanism that is not primarily related to oxygen radical-mediated damage. Formation of DHBT-1 requires only dopamine, l-cysteine, and an oxidizing environment, conditions that may well exist in the cytoplasm of neuromelanin-pigmented dopaminergic neurons in the parkinsonian substantia nigra. The results of this study raise the possibility that DHBT-1 might be an endotoxin formed specifically in pigmented dopaminergic neurons that can contribute to irreversible damage to mitochondrial complex I and substantia nigra cell death in Parkinson's disease.
    Type of Medium: Electronic Resource
    URL: http://dx.doi.org/10.1046/j.1471-4159.1997.69041530.x
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