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Digitale Medien

Evidence for sequential degeneration of the neurons in the intermediate zone of the spinal cord in amyotrophic lateral sclerosis: a topographic and quantitative investigation (1989)

Oyanagi, K. ; Ikuta, F. ; Horikawa, Y.

Springer

Acta neuropathologica 77 (1989), S. 343-349

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ISSN: 1432-0533

Schlagwort(e): ALS ; Spinal cord ; Propriospinal neuron ; Anterior horn cell ; Quantitative study

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary To elucidate the degenerating mechanism of the neurons in the intermediate zone of the spinal cord in classical amyotrophic lateral sclerosis (ALS), the spinal neurons in a patient with ALS, whose muscular strength was fairly well preserved up to death, were examined quantitatively and topographically, and compared with the data of advanced ALS patients and age-matched control subjects reported previously. In advanced ALS patients, anterior horn cells completely disappeared and the medium-sized (nuclear area; 71–150 μm2) and large (nuclear area; greater than 151 μm2) neurons in the intermediate zone were severely reduced. In the present case, however, the loss of anterior horn cells was severe but the degree was not equal to that of advanced ALS patients, and the neurons in the intermediate zone were quite well preserved. The finding indicates that the primary degeneration may occur in the anterior horn cells and the neurons in the intermediae zone degenerate sequentially in the spinal gray matter in ALS.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00687368

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Digitale Medien

Nafion-like thin film plasma-polymerized from perfluorobenzene/SO2 mixture (1989)

Inagaki, N. ; Tasaka, S. ; Horikawa, Y.

Bognor Regis [u.a.] : Wiley-Blackwell

Journal of Polymer Science Part A: Polymer Chemistry 27 (1989), S. 3495-3501

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ISSN: 0887-624X

Schlagwort(e): Chemistry ; Polymer and Materials Science

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Chemie und Pharmazie

Notizen: Plasma polymerization of perfluorobenzene/sulfur dioxide (PFB/SO2) mixture was investigated by elemental analysis, infrared spectroscopy, and XPS. Plasma polymer films like Nafion were obtained from the plasma polymerization of PFB/SO2 mixture. The plasma polymerization deposited fluoropolymers with sulfur moieties including sulfonate and sulfonic acid groups. The elemental composition, F/C, and S/C atomic ratio of the formed plasma polymers were 0.65-0.67 and 0.24-0.27, respectively, which were independent of the starting mixture composition. The polymers showed cation-exchange ability of which the capacity was 0.49 meq/g polymer, and initiated the polymerization of pyrrole.

Zusätzliches Material: 3 Ill.