ISSN:
1432-198X
Keywords:
Glomerulonephritis
;
Factor H
;
Complement
;
β-1 H globulin
;
Collagen type III glomerulopathy
Source:
Springer Online Journal Archives 1860-2000
Topics:
Medicine
Notes:
Abstract A non-immune complex-mediated glomerulonephritis associated with persistent hypocomplementemia occurred in a young boy. Measurement of complement components revealed complete factor H deficiency, inherited as an autosomal recessive trait. Evaluation of the renal lesion revealed extensive deposition of type III collagen suggestive of collagen type III glomerulopathy, a recently identified cause of chronic renal insufficiency in children and adults. This report represents the first association of inherited factor H deficiency with collagen type III glomerulopathy.
Type of Medium:
Electronic Resource
URL:
http://dx.doi.org/10.1007/BF00858956
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