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Digitale Medien

Small diameter polyurethane-polydimethylsiloxane vascular prostheses made by a spraying, phase-inversion process (1992)

Soldani, G. ; Panol, G. ; Sasken, H. F. ; [weitere]

Springer

Journal of materials science 3 (1992), S. 106-113

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Details

ISSN: 1573-4838

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin , Technik allgemein

Notizen: Abstract A highly porous, distensible, gel-like tubular membrane suitable for a small diameter arterial prosthesis was fabricated by combining techniques for spraying and phase-inversion of thermodynamically unstable solutions of a biocompatible polyurethane (PU)-polydimethylsiloxane (PDMS) blend (CardiothaneTH51) over a sliding and rotating mandrel. The cylindrical membrane was characterizedin vitro for mechanical, morphological and permeability properties, and evaluatedin vivo as a 1.5 mm internal diameter prosthesis for the replacement of the rat abdominal aorta. A mature, stable luminal interface, a thin internal capsule without anastomotic hyperplasia, and the deposition of collagen within the voids of the polymer mesh were observed after 8 weeks of implantation.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00705277

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