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Digitale Medien

Renin measurement in blood collected from the efferent arteriole of the kidney of the rat (1975)

Johnston, C. I. ; Matthews, P. G. ; Davis, J. M. ; [weitere]

Springer

Pflügers Archiv 356 (1975), S. 277-286

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Details

ISSN: 1432-2013

Schlagwort(e): Renin ; Efferent Arteriole ; Feedback Control ; Macula densa ; Angiotensin

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Plasma renin could be detected in 16 nl of rat plasma by incubating at 50°C, pH 6.2 with 20 μl of a rat renin substrate. In 60 nl samples it could be estimated and differences in concentration of 20% could be detected. Plasma renin concentration was measured in blood from the superficial efferent arterioles of a rat's kidney. The concentrations of renin in different efferent arterioles of the same rat were similar. The renin concentration of efferent arteriolar blood was 361±189 (S.D.) ng Al ml−1 (blood) hour−1 which was not different from the renin concentration of simultaneously taken femoral artery blood (340±217). Plasma renin concentration can be measured in efferent arteriolar blood and will allow the control of renin secretion to be studied.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00583839

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