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Digitale Medien

The BFM-protocol for HIV-negative Burkitt's lymphomas and L3 ALL in adult patients: a high chance for cure (1992)

Pees, H. W. ; Radtke, H. ; Schwamborn, J. ; [weitere]

Springer

Annals of hematology 65 (1992), S. 201-205

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Details

ISSN: 1432-0584

Schlagwort(e): Burkitt's lymphoma ; Acute lymphoblastic leukemia, B-type ; Tumor lysis syndrome

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary During a period of 9 years we used the pediatric BFM-NHL protocol for treatment of 14 adult patients with Burkitt's lymphoma or L3 acute lymphoblastic leukemia. Ten of 14 patients obtained a complete remission including 5/8 with stage-IV disease or B-ALL. After a median follow-up of 55 months none of these ten patients relapsed. The projected survival after 8 years is 71%. Toxicity was moderate, with one early death; a tumor lysis syndrome occurred in four patients. From our experience we conclude that the BFM-NHL protocol is very effective in adult patients, with a high cure rate and acceptable toxicity, even in advanced stages of disease.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01703945

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