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1

Digitale Medien

The unusual afterglow of the γ-ray burst of 26 March 1998 as evidence for a supernova connection (1999)

Kulkarni, S. R. ; Djorgovski, S. G. ; Eichelberger, A. C. ; [weitere]

[s.l.] : Macmillian Magazines Ltd.

Nature 401 (1999), S. 453-456

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ISSN: 1476-4687

Quelle: Nature Archives 1869 - 2009

Thema: Biologie , Chemie und Pharmazie , Medizin , Allgemeine Naturwissenschaft , Physik

Notizen: [Auszug] Cosmic γ-ray bursts have now been firmly established as one of the most powerful phenomena in the Universe, releasing almost the rest-mass energy of a neutron star within the space of a few seconds (ref. 1). The two most popular models to explain γ-ray bursts are ...

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1038/46744

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2

Digitale Medien

Therapeutic application of various immunostimulators on the L2C guinea-pig leukemia (1978)

Klein, D. L. ; Brown, W. ; Cote, P. ; [weitere]

Springer

Cancer immunology immunotherapy 4 (1978), S. 229-237

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ISSN: 1432-0851

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Immunostimulators such as Corynebacterium parvum (C. parvum), Bacillus Calmette-Guerin (BCG), pyran copolymer, and glucan were examined in the guinea pig L 2 C lymphoblastic leukemia model to determine their capacity for therapeutic modulation of the immune response of the host toward controlling leukemic cell proliferation. The dose, route, and frequency of administration of the stimulators were also evaluated as a function of time in order to obtain an optimal antileukemic effect. Results indicated that only C. parvum and BCG were capable of significantly increasing host survival when given 1 day after an inoculation of 1.5×10 4 viable leukemic cells. Administration of BCG or C. parvum, alone or in combination with irradiated blast cells on either days 4 or 7, was totally ineffective in prolonging survival. In the majority of cases, enhanced leukemic growth was observed on these days. The combination of BCG and/or C. parvum with irradiated syngeneic blast cells given 24 h after leukemia inoculation promoted a synergistic response with a significant increase in median survival time and a number of long-term survivors.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00200153

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3

Digitale Medien

Chemo-adoptive immunotherapy against a guinea-pig leukemia (1979)

Klein, D. L. ; Brown, W. ; Cote, P. ; [weitere]

Springer

Cancer immunology immunotherapy 6 (1979), S. 17-25

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ISSN: 1432-0851

Quelle: Springer Online Journal Archives 1860-2000

Thema: Medizin

Notizen: Summary Strain-2 guinea-pigs bearing the transplantable L2C leukemia were treated with cytoxan 24 h prior to receiving an injection of either allogeneic or syngeneic spleen cells from donors preimmunized to the leukemia. Treatment with the drug alone produced a remission period which lasted for 4–5 weeks before eventual relapse and death. An IP transfer of spleen or peritoneal exudate (PE) cells from syngeneic strain-2 guinea-pigs hyperimmunized to the leukemia greatly extended the survival times of drug-treated animals beyond that observed in animals receiving normal strain-2 cells. Long-term survivors were refractory to a subsequent challenge with a lethal inoculum of L2C cells. A reduced tumor load was essential for an immunotherapeutic effect of adoptively transferred cells. The use of sensitized lymphocytes alone failed to control the established disease. Hyperimmune spleen cells from strain-13 and Hartley guinea-pigs also demonstrated a slight capacity to inhibit the proliferation of leukemia cells when injected into diseased animals previously treated with the drug. Due to inadequate drug suppression, however, the injection of allogeneic cells from either immune strain-13 or Hartley guinea-pigs did not prolong the latent period for the appearance of the leukemia to the same extent as either immune strain-2 spleen or PE cells. A marked delay in the onset of disease was noted when immune spleen cells from either syngeneic or allogeneic sources were mixed in vitro with L2C leukemia cells at a ratio of 200:1 before injection back into normal strain-2 animals. However, an exposure of L2C blast cells in vitro with heat-inactivated serum obtained from L2C-immune strain-2 animals significantly enhanced the onset of disease.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF00206012

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4

Digitale Medien

Field test and evaluation of residential sprinkler systems: Part II (1984)

Arthur, E. ; Cote, P. E.

Springer

Fire technology 20 (1984), S. 48-58

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ISSN: 1572-8099

Schlagwort(e): Residential sprinkler systems ; fire control ; survivability criteria ; obscuration ; carbon monoxide ; fire tests

Quelle: Springer Online Journal Archives 1860-2000

Thema: Architektur, Bauingenieurwesen, Vermessung

Notizen: Abstract A series of National Fire Protection Association full-scale tests involving sprinkler installations was conducted in a two-story residence in Los Angeles, CA, and in a mobile home in Charlotte, NC. Previous laboratory tests, including full-scale room fire tests, had indicated that a prototype “quick-response” sprinkler was effective in controlling residential home fires. More full-scale fire tests under less controlled and more operational conditions were considered necessary to confirm or deny this conclusion. Part I of this three-part series (November 1983) explained the objectives of the tests and the test procedures that were to be followed. This second part describes the criteria used to evaluate the effectiveness of sprinkler systems using the “quick response” sprinkler in the series of seventy-six tests and the results of those tests. Part III will cover that phase of the test program that focused on a comparison of sprinkler and smoke detector activation times in the mobile home test structure.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF02390047

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5

Digitale Medien

Field test and evaluation of residential sprinkler systems: Part III (1984)

Arthur, E. ; Cote, P. E.

Springer

Fire technology 20 (1984), S. 41-46

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ISSN: 1572-8099

Schlagwort(e): Mobile home ; sprinklers ; smoke detector ; fire tests

Quelle: Springer Online Journal Archives 1860-2000

Thema: Architektur, Bauingenieurwesen, Vermessung

Notizen: Abstract A series of full-scale fire tests utilizing prototype “quick-response” sprinklers was conducted in a two-story residence in Los Angeles, CA, and a mobile home in Charlotte, NC. A prime objective of the program was to test the performance of alternative sprinkler designs to “control” the development of fire in single-family dwellings and mobile homes. Part of the mobile home test series focused on a study of the comparative activation times of sprinklers and smoke detectors installed in the same areas under a variety of test conditions. The results of that phase of the test program are given here.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF02384149

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6

Digitale Medien

Absence of external E-field effects on transformations in steels (1992)

Cote, P. J. ; Meisel, L. V. ; Hickey, T.

Springer

Journal of materials science 27 (1992), S. 2048-2052

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ISSN: 1573-4803

Quelle: Springer Online Journal Archives 1860-2000

Thema: Maschinenbau

Notizen: Abstract Large hardness increases were recently reported for an ASTM A723 steel and a tool steel when a 1 kVcm−1 external electric field was applied during the post-austenitization quench. The increased hardness was attributed to a field-induced order-of-magnitude decrease in the austenite decomposition rate during the quench. The results of an extensive study of austenite decomposition kinetics in the same A723 steel and a similar tool steel in the presence and absence of electric fields of magnitudes up to 3 kVcm−1 during post-austenitization cooling are reported here. Differential thermal analysis and thermomagnetic analysis were employed to directly monitor the austenite decomposition processes in both steels. Supplementary hardness measurements in the tool steel are also reported. No effects of external electric fields on austenite transformations were detected.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1007/BF01117916

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7

Digitale Medien

L'action de l'ammoniac sur l'oxyde cuivrique. et les hydroxo-complexes de cuivre (II) (1970)

Gübeli, A. O. ; Hébert, J. ; Cǒté, P. A. ; [weitere]

New York, NY : Wiley-Blackwell

Helvetica Chimica Acta 53 (1970), S. 186-197

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ISSN: 0018-019X

Schlagwort(e): Chemistry ; Organic Chemistry

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Chemie und Pharmazie

Notizen: Using a new mathematical treatment, the nature and stability constants of the simple and mixed complex-species of copper(II) with hydroxyde and ammonia as ligands have been determined. The solubility curves of CuO in heterogeneous equilibrium have been identified in function of pH only and in function of pH and pNH3tot at 25° and unit ionic strength (NaClO4).The predominent species in the relatively dilute system limited by the ionic strength are [Cu2+], [Cu(OH)2], [Cu(OH)3-], [Cu(OH)42-], [Cu(NH3)22+], [Cu(NH3)32+], [Cu(NH3)42+], [Cu(NH3) (OH)+], [Cu(NH3)3(OH)+] and [Cu(NH3)2(OH)2].

Zusätzliches Material: 4 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/hlca.19700530126

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8

Digitale Medien

L'action de l'ammoniac sur l'hydroxyde de cobalt(II) et la stabilité des complexes en milieu aqueux (1970)

Gübeli, A. O. ; Hébert, J. ; Taillon, R. ; [weitere]

New York, NY : Wiley-Blackwell

Helvetica Chimica Acta 53 (1970), S. 1229-1235

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ISSN: 0018-019X

Schlagwort(e): Chemistry ; Organic Chemistry

Quelle: Wiley InterScience Backfile Collection 1832-2000

Thema: Chemie und Pharmazie

Notizen: From the solubility of precipitated Co(OH)2 (s) determined radiometrically as a function of pH and ammonia content of the heterogeneous systems, the formation constants have been obtained for the following mononuclear hydroxo-, ammine- and mixed hydroxo-ammine-complexes: Co(OH)2, Co(OH)3-, Co(NH3)22+, Co(NH3)32+, Co(NH3)42+ and Co(OH)2 (NH3)2. The solubility of cobalt(II) hydroxide has also been calculated. The medium was 1M NaClO4 and the temperature 25° C.

Zusätzliches Material: 3 Ill.

Materialart: Digitale Medien

URL: http://dx.doi.org/10.1002/hlca.19700530542

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