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  • 1
    ISSN: 1420-9098
    Keywords: Key words: Colony foundation, Belonogaster, Polistinae.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary: The development of colony foundations of Belonogaster juncea juncea(Fab.) was studied both in the field (Messa quarter, Yaoundé, Cameroun) and in captivity (University of Florence, Italy). Colonies were first initiated by single females who could be joined by other foundresses (2 to 8) coming, in their great majority, from the same maternal colony as the initial foundress female. The co-foundresses remained faithful to one single colony or joined other colonies originating from the same maternal colony and remained, preferentially, on those with the more advanced immature brood. In most cases the nest starter turned out to be the dominant female and her position was usurped in only four cases. Only 25 % of the haplometrotic foundations reached the post-emergence phase while it was reached by 56.7 % of the associative foundations. Only the latter succeeded in producing sexuals. The division of labour between associated females is similar to that observed in other social wasps with dominant individuals who are seldom absent from the nest, lay eggs and perform abdominal vibrations and subordinate individuals that are active foragers. The possibility of a swarming colony foundation in this species is briefly discussed.
    Type of Medium: Electronic Resource
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  • 2
    ISSN: 0378-1119
    Keywords: DNA footprinting ; Recombinant DNA ; chloramphenicol acetyltransferase assay ; gene regulation ; transcription factor Sp1
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Biology
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1365-3083
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: The potential leishmanicidal activity of interleukin-15 (IL-15) was examined while priming with the cytokine phorbol-myristate-acetate (PMA)-activated macrophages and infecting them with Leishmania infantum parasites. The activation of macrophage cultures with IL-15 determined a significant anti-leishmanial activity, comparable with that induced by interferon-gamma (IFN-γ). The killing of Leishmania in macrophages primed with IL-15, as well as with IFN-γ, was followed by an increase in the IL-12 synthesis. The neutralization of IL-15 or IFN-γ, by specific monoclonal antibodies (MoAb) caused a significant reduction in leishmanicidal activity. Furthermore, in PMA-activated macrophages, the neutralization of IL-12 production by a specific anti-IL-12 MoAb reduced leishmanicidal activity induced by IL-15 and IFN-γ. Data indicate that IL-15 could have a role as an activator of leishmanicidal activity, directly or indirectly, by inducing IL-12 production.
    Type of Medium: Electronic Resource
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  • 4
    ISSN: 1432-5411
    Source: Springer Online Journal Archives 1860-2000
    Topics: Physics
    Notes: Abstract An analysis of thed-α coincidence spectra of the7Li(3He, αd)4He reaction at incident energy of 5.0 MeV and at various detector angles has been carried out. The values of the spectroscopic parameters of theJ π=1+,T=06Li state at excitation energy of 5.65 MeV have been deduced. The results, considering the experimental errors, do not appear to be dependent on the geometry and are in line with the ones adopted in literature.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1434-9949
    Keywords: Androgens ; Cortisol ; Rheumatoid Arthritis ; Disease Activity
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Summary Androgen status and the role played by androgens in the pathogenesis of rheumatoid arthritis (RA) in female patients are a matter of debate. In the present study serum testosterone (T), DHEAS, sex hormone binding globulin (SHBG) and cortisol levels were determined in 55 RA women, both in pre- and post-menopausal (M) status, and in a group of healthy subjects. Patients were divided into two groups according to disease activity and a correlation analysis of hormonal levels against serum IL1β levels was performed. No significant differences were found in serum T levels between RA patients and controls, both in preM (1.38±0.4 vs 1.35±0.3 nmol/l; p=ns) and in postM status (1.21±0.2 vs 1.10±0.2 nmol/l; p=ns). Serum SHBG levels were lower in RA patients than in control subjects, both in pre and in postM status. DHEAS levels were significantly lower in preM RA patients than in controls (2.34±1.2 vs 5.93±1.6 µmol/l; p〈0.001) while cortisol levels were significantly higher in preM active RA patients than in controls (466.2±30.3 vs 411±66.2 nmol/l; p=0.02). IL1β levels were significantly higher in RA patients than in controls both in pre- and postM subjects (70±33.8 vs 23.1±2.9 and 92±27.4 vs 31.9±3.1 fmol/l, p〈0.001, respectively). Although androgen status could play a role in the pathogenesis of RA, at present it is not possible to exclude the influence of RA itself on sex hormone profile.
    Type of Medium: Electronic Resource
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  • 6
    ISSN: 0951-4198
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: The accurate molecular weights for a series of 37 unknown synthetic peptides, used in research studies involving synthetic vaccines, antibacterial peptides or the de novo design of helical peptides and proteins, were determined with a magnetic sector instrument. All data were obtained with external calibration over a wide mass range during magnetic scanning. Errors between observed and theoretical monoisotopic molecular weights were typically in the 5-60 ppm range for the unknowns at sector resolutions between 2500 and 9000 (10% valley). Isotopic clusters for charge states up to 10+ were resolved through the use of high resolution. Collisionally activated dissociation (CAD) in the electrospray interface resulted in product ions that enabled either full or partial sequencing of most unknown peptides of molecular weights below 2000 Da. The complete primary sequence for one peptide was determined and the importance of high resolution was demonstrated by the differentiation of lysine from glutamine, two amino acids differing in residue mass by only 0.0364 Da. Two other peptides, with identical monoisotopic masses, but different primary sequences, were differentiated based on CAD-MS data.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    New York, NY : Wiley-Blackwell
    Rapid Communications in Mass Spectrometry 6 (1992), S. 717-718 
    ISSN: 0951-4198
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Physics
    Notes: Chemical weapons use, although prohibited by the 1925 Geneva Protocol, has been reported in several armed conflicts including the Iran/Iraq war. The use of these weapons during this conflict and the concern over possible use of chemical warfare (CW) agents during the Persian Gulf war has heightened international awareness and prompted many nations to pursue with incresed vigour the signature of a new Chemical Weapons Convention. The most recent draft of the Chemical Weapons Convention contains a number of provisions aimed at developing a treaty that will enable nations to ensure compliance by all signatory nations. Compliance monitoring will be required in a number of scenarios, including the verification of alleged use, the storage and destruction of chemical weapons stocks and ensuring that industrial sites are not illegally producing CW agents. It follows from this draft treaty that compliance monitoring will require a high level of sophisticated analytical support to ensure the establishment of an enforceable treaty. The United Nations Conference on Disarmament therefore formed a multi-national Technical Group on Instrumentation to address the analytical challenges confronting signatory nations.
    Additional Material: 4 Ill.
    Type of Medium: Electronic Resource
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  • 8
    Electronic Resource
    Electronic Resource
    Chichester : Wiley-Blackwell
    Biological Mass Spectrometry 18 (1989), S. 484-491 
    ISSN: 0887-6134
    Keywords: Chemistry ; Analytical Chemistry and Spectroscopy
    Source: Wiley InterScience Backfile Collection 1832-2000
    Topics: Chemistry and Pharmacology
    Notes: Capillary column gas chromatography/mass spectrometry, under electron impact and chemical ionization conditions, was used for the detection and identification of mustard and other sulfur vesicant-related decomposition products in a number of aqueous sample extracts. Interpretation of the mass spectral, infrared, chromatographic and trimethylsilyl derivatization data acquired during this study enabled the identification of nineteen sulfur vesicant-related hydrolysis products. Many of the compounds characterized during these analyses, including a number of ether/thioether macrocycles and vinyl alcohols, have either not been previously reported or have not been previously associated with the decomposition of munitions-grade mustard.
    Additional Material: 6 Ill.
    Type of Medium: Electronic Resource
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