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  • 1
    Publication Date: 2021-12-09
    Description: We report our progress on the project for solving larger scale quadratic assignment problems (QAPs). Our main approach to solve large scale NP-hard combinatorial optimization problems such as QAPs is a parallel branch-and-bound method efficiently implemented on a powerful computer system using the Ubiquity Generator(UG) framework that can utilize more than 100,000 cores. Lower bounding procedures incorporated in the branch-and-bound method play a crucial role in solving the problems. For a strong lower bounding procedure, we employ the Lagrangian doubly nonnegative (DNN) relaxation and the Newton-bracketing method developed by the authors’ group. In this report, we describe some basic tools used in the project including the lower bounding procedure and branching rules, and present some preliminary numerical results. Our next target problem is QAPs with dimension at least 50, as we have succeeded to solve tai30a and sko42 from QAPLIB for the first time.
    Language: English
    Type: reportzib , doc-type:preprint
    Format: application/pdf
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  • 2
    Publication Date: 2022-05-13
    Description: 二次割当問題は線形緩和が弱いことが知られ,強化のため多様な緩和手法が考案されているが,その一つである二重非負値計画緩和( DNN 緩和)及びその解法として近年研究が進んでいるニュートン・ブラケット法を紹介し,それらに基づく分枝限定法の実装及び数値実験結果について報告する.
    Language: Japanese
    Type: reportzib , doc-type:preprint
    Format: application/pdf
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  • 3
    Electronic Resource
    Electronic Resource
    College Park, Md. : American Institute of Physics (AIP)
    The Journal of Chemical Physics 110 (1999), S. 1662-1668 
    ISSN: 1089-7690
    Source: AIP Digital Archive
    Topics: Physics , Chemistry and Pharmacology
    Notes: The isomerization rate of 2-(2-propenyl)anthracene (22PA) in the lowest excited singlet (S1) state was investigated in supercritical fluids (SCF); ethane and CO2, as well as in a series of liquid n-alkanes at high pressures. Combining the present results with our preceding ones which had been examined in compressed liquid n-alkane solvents [J. Phys. Chem. A 101, 2240 (1997)] we completed the curve of forward isomerization rate constant (kf) against solvent viscosity (η) over the entire friction range. We also discuss the dependence of kf on the inverse of solvent self-diffusion coefficient (D−1), which is used as a measure of solvent collisional frequency. The Kramers turnover behavior of 22PA thus observed was compared with our previous result of 2-vinylanthracene [J. Chem. Phys. 103, 5548 (1995)]. The kf values of both isomerization reactions around the turnover viscosity region never attains those which are predicted by transition state theory. © 1999 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Oxford, UK : Blackwell Publishing Ltd
    International journal of urology 4 (1997), S. 0 
    ISSN: 1442-2042
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background We reviewed the functional outcome and late complications of continent urinary reservoirs (CUR) constructed with a cecocolonic segment, including the Indiana pouch, in 37 patients treated in our clinic. Methods The CUR procedure was performed on 37 patients, creating partially detubularized (PD) reservoirs in 9 patients, totally detubularized (TD) reservoirs in 16 patients and reservoirs with an ileal patch (IP) in 12 patients. Continence was achieved by the nipple valve in 10 patients and by ileal plication in 27 patients. The mean follow-up period was 46 months (range, 15 to 87 months). The function of the reservoir was evaluated by measurement of the intrareservoir pressure. Results Patients with the TD reservoir had less frequent appearance of involuntary, phasic elevation of the intrareservoir pressure (30.8%) than those with the PD reservoir (62.5%). In contrast, this phasic elevation was found in only 1 patient with an IP reservoir. The IP reservoir had the largest capacity accompanied by the lowest maximum intrareservoir pressure. Total incontinence was observed in 2 patients with ileal plication due to disruption of the plicated sutures on the terminal ileum. Frequent difficulty in catheterizing the reservoir was found in 2 patients, and reservoir-ureter reflux was found in 3 renal units. The serum chloride level was significantly elevated after surgery, however, in most patients the levels remained within normal limits. Conclusion Our experience of the outcome and late complications of reservoirs indicates that the cecocolonic reservoir with an ileal patch and stapled ileal plication, i.e., the Indiana pouch, is a better choice for continent urinary diversion for patients who need a cystectomy.
    Type of Medium: Electronic Resource
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  • 5
    ISSN: 1442-2042
    Source: Blackwell Publishing Journal Backfiles 1879-2005
    Topics: Medicine
    Notes: Background Men with acquired hypogonadotropic hypogonadism (AHH) who desire restoration of fertility are treated with exogenous gonadotropin. However, gonadotropin (Gn) therapy does not always restore testicular function. It is unknown whether the therapeutic responses to Gn therapy correlate with their testicular histological findings. Thus, we analyzed factors influencing testicular dysfunction and therapeutic responses in AHH. Methods Of 21 men with AHH, 11 had no postmeiotic germ cells and were classified as the severe spermatogenic failure group. These were compared with the other 10 patients who had postmeiotic germ cells and comprised the mild spermatogenic failure group. Results: Testicular volume and tubular diameter were significantly smaller, and the basement membrane and tunica propria were significantly thicker in the severe failure group. The gonadotropin basal level and response to exogenous gonadotropin-releasing hormone, and the testosterone response to exogenous human chorionic gonadotropin were significantly lower in the severe failure group of patients. Also, the recovery of spermatogenesis and testosterone secretory potentials was poor in the cases with a duration between diagnosis and treatment of 2 years or more. Conclusion Longer periods without treatment may be responsible for irreversible testicular dysfunction in AHH. Gn therapy should be initiated very soon after the diagnosis of AHH if fertility is desired.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    [S.l.] : American Institute of Physics (AIP)
    Journal of Applied Physics 88 (2000), S. 3235-3241 
    ISSN: 1089-7550
    Source: AIP Digital Archive
    Topics: Physics
    Notes: By polarized infrared absorption spectroscopy, we have determined the relation between the molecular orientation of a rubbed polyimide film and that of a very thin liquid crystal (LC) layer (approximately a monolayer of 8CB molecules) in contact with the polyimide film. The molecular orientation of the rubbed polyimide film was determined by fitting theoretically the incident angle dependence of the infrared absorption for molecular vibrations polarized parallel to the length of the polymer. Approximately a monolayer of 8CB molecules was deposited on a rubbed polyimide film with previously measured molecular orientation. The molecular orientation of this LC layer was also determined by polarized infrared absorption. We found that the LC molecules and the polyimide chains are oriented, on average, along the rubbing direction and tilted up from the surface, and that the molecular order of the LC layer is higher than that of the underlying rubbed polyimide film. © 2000 American Institute of Physics.
    Type of Medium: Electronic Resource
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  • 7
    ISSN: 1435-5922
    Keywords: Key words: superparamagnetic iron oxide (SPIO) ; hepatocellular carcinoma (HCC) ; magnetic resonance imaging (MRI)
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract: The tumor-detecting capacity and clinical usefulness of superparamagnetic iron oxide (SPIO) magnetic resonance imaging (MRI) were examined in patients with hepatocellular carcinoma. The tumor detection rate of SPIO-MRI (64.5%) was comparable to those of dynamic computed tomography (CT) and plain MRI, but lower than that for Gd dynamic MRI (93.5%; P 〈 0.01%). A combination of Gd dynamic MRI and SPIO-MRI improved the detection rate; further, the tumor stage with respect to tumor blood-flow pattern was predicted by combining plain MRI with SPIO-MRI. This combination procedure may also be useful for selecting therapeutic strategies.
    Type of Medium: Electronic Resource
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