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  • 1
    ISSN: 1432-1440
    Keywords: Meningoencephalitis ; Mycobacterium avium intracellulare infection ; Mycobacterium avium intracellulare drug therapy ; AIDS
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract A wide variety of pathologies afflicting the CNS is see in patients infected with the human immunodeficiency virus. We report the case of relapsing meningoencephalitis caused by Mycobacterium avium intracellulare (MAI) in a homosexual male with the acquired immunodeficiency syndrome in whom repeated use of polymerase chain reaction was required to detect MAI-specific DNA in the cerebrospinal fluid. Successful responses to early empirical antibiotic combination treatment, including the drugs clarithromycin and rifabutin, were demonstrated by clinical, EEG, and CSF improvement during an 8-month period. To our knowledge, this study presents the first known patient with the acquired immunodeficiency syndrome effectively treated for MAI meningoencephalitis and suggests that modern antimycobacterial combination therapy may improve the poor prognosis of CNS infections with nontuberculous myoobacteria.
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Thermochimica Acta 80 (1984), S. 11-21 
    ISSN: 0040-6031
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Chemistry and Pharmacology
    Type of Medium: Electronic Resource
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  • 3
    ISSN: 1433-0407
    Keywords: Schlüsselwörter Elektrokrampfbehandlung ; Ältere Patienten ; Depression ; Nutzen ; Risiken ; Key words Electroconvulsive therapy ; Elderly patients ; Depression ; Benefits ; Risks
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Description / Table of Contents: Summary Between January 1995 and June 1996, 24 inpatients at our hospital (mean age 55.6 years) were treated with electroconvulsive therapy (ECT). Clinical improvement was observed in 80% of the patients, including those without risk factors (NRG, n=16), as well as those with concomitant cardiovascular diseases (RG, n=8). During a mean period of observation of 224 days after the end of ECT 7 patients (35%) relapsed. The rate of relapse was higher in RG than in NRG patients (57.1 vs 23.1%). In all cases ECT was well tolerated; 285 applications of ECT did not result in mortality or persistent morbidity. However, RG patients may be at increased risk for the development of minor cardiovascular complications, which were noted in three RG patients (37.5%), but only in one patient (6.2%) in the NRG (Fisher’s test, P=0.09). Taken together, our results demonstrate that ECT is a safe treatment regimen for depression even in medically ill patients of old age.
    Notes: Zusammenfassung Vierundzwanzig Patienten (Altersdurchschnitt 55,6 Jahre) wurden im Zeitraum 1/95 bis 6/96 an unserer Klinik mit der Elektrokrampftherapie (EKT) behandelt. Sowohl Risikopatienten mit kardiovaskulären Begleiterkrankungen (RG, n=8) als auch Patienten mit p.d. nicht erhöhtem Risiko (NRG, n=16) zeigten in über 80% der Fälle eine klinische Besserung. Bei 7 (35%) dieser Patienten kam es während des mittleren Beobachtungszeitraumes von 224 Tagen nach Abschluß der 1. EKT-Serie zu einer erneuten Exazerbation der psychischen Störung. Dabei zeigten RG-Patienten eine höhere Rückfallquote im Vergleich zu Patienten der NRG (57,1% vs. 23,1%). In allen Fällen konnte die EKT regulär beendet werden; bei insgesamt 285 durchgeführten EKT traten keine schwerwiegenden Komplikationen auf. Allerdings hatten RG-Patienten im Vergleich zu Patienten der NRG ein höheres Risiko für das Auftreten geringfügiger kardialer Komplikationen (37,5% vs. 6,2%, Fisher’s Test p=0,09). Zusammenfassend demonstrieren unsere Ergebnisse, daß die EKT auch bei Risikopatienten eine sichere Behandlungsmethode ist.
    Type of Medium: Electronic Resource
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