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  • 1
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Physica B+C 146 (1987), S. 379-397 
    ISSN: 0378-4363
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 2
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Physica B+C 108 (1981), S. 1109-1110 
    ISSN: 0378-4363
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 3
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Physica B+C 114 (1982), S. 167-173 
    ISSN: 0378-4363
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 4
    Electronic Resource
    Electronic Resource
    Amsterdam : Elsevier
    Physica B: Physics of Condensed Matter 154 (1988), S. 116-124 
    ISSN: 0921-4526
    Source: Elsevier Journal Backfiles on ScienceDirect 1907 - 2002
    Topics: Physics
    Type of Medium: Electronic Resource
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  • 5
    Electronic Resource
    Electronic Resource
    Springer
    Insectes sociaux 36 (1989), S. 277-292 
    ISSN: 1420-9098
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Description / Table of Contents: Zusammenfassung Eine obligatorisch monogyne und eine fakultativ polygyne Form vonCamponotus nawai Ito wurden vergleichen. Jahreszeitliche Veränderungen der Koloniezusammensetzung waren bei beiden Formen ähnlich, abgesehen von der Zeit, in der geflügelte Geschlechtstiere in den Nestern zu finden sind. Die Sammelergebnisse lassen annehmen, daß bei der monogynen Form neue Kolonien nur von einzelnen Königinnen gegründet werden, während sie bei der polygynen Form durch Kolonieteilung entstehen. In polygynen Völkern waren alle oder fast alle Königinnen fertil, sa daß eine funktionelle Polygynie vorliegt. Königinnen der monogynen Form sind größer und haben größere Ovarien. Die Königinnen der polygynen Form zeigen eine bimodale Grossen-verteilung doch sind die kleineren Königinnen seltener. Bei der polygynen Form war die Anzahl der Königinnen mit der Menge der Brutstadien positiv korreliert, aber negativ mit der Menge der Brustadien pro Königin. Anscheinend besiedelt die polygyne Form mehr nördliche Gebiete als die monogyne, ihre Areale überschneiden sich kaum. Aufgrund der jahreszeitlich verschiedenen Schwarmzeiten sind die monogyne und die polygyne Form vonC. nawai möglicherweise zwei verschiedene Arten.
    Notes: Summary Obligately monogynous and facultatively polygynous forms ofCamponotus nawai Ito was compared. The seasonal changes of colony composition were similar in the two forms except for the season in which alates were found in nests. Collection data suggested that new colonies are founded only by single foundresses in the monogynous form, but mainly by colony budding in the polygynous form. All or most queens in polygynous nests were fertile, thus polygyny is functional. The body size and ovarian volume of queens were larger in the monogynous forms. Queens of the polygynous form showed bimodal size distribution, though smaller queens were less frequent. In the polygynous form, the number of queens was positively correlated with the number of immatures, but negatively correlated with the number of immatures per queen. It seems that the polygynous form occupies more northern regions than the monogynous one and their ranges contact parapatrically. The monogynous and polygynous forms ofC. nawai may be different species because of the differing mating seasons.
    Type of Medium: Electronic Resource
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  • 6
    Electronic Resource
    Electronic Resource
    Springer
    Insectes sociaux 38 (1991), S. 37-44 
    ISSN: 1420-9098
    Keywords: Monogyny ; polygyny ; queen behavior ; Camponotus
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Behavioral differences of queens of the obligately monogynous and facultatively polygynous forms ofCamponotus nawai complex were examined. Queens of the monogynous form were groomed by and received food from workers more frequently but they walked about inside nests less frequently than queens of the polygynous form. Hierarchical relationships were not observed among queens of polygynous nests. In general, those queens were equally cared for by workers, aggregated around the center of nests, and showed no hostility toward each other.
    Type of Medium: Electronic Resource
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  • 7
    Electronic Resource
    Electronic Resource
    Springer
    Insectes sociaux 43 (1996), S. 217-226 
    ISSN: 1420-9098
    Keywords: Pleometrosis ; relatedness of cofoundresses ; Polyrhachis ; DNA fingerprinting
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology
    Notes: Summary Field studies ofPolyrhachis moesta revealed that colonies were facultatively founded by more than one queen, even though each established colony was inhabited by only one queen with her workers. In pleometrotic colonies, it was found that cofoundresses frequently exhibited cooperative behaviors, including trophallaxis. The results of DNA fingerprinting showed that multiple foundresses were not genetically to one another. It seems that they aggregate randomly and independently of their relatedness. A discussion of the reasons why foundresses ofP. moesta do not aggregate preferentially with genetically related females.
    Type of Medium: Electronic Resource
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  • 8
    ISSN: 1432-0428
    Keywords: Keywords MODY ; HNF-1α ; insulin ; arginine ; mutation.
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract Aims/hypothesis. Mutations in the hepatocyte nuclear factor-1α gene are a common cause of the type 3 form of maturity-onset diabetes of the young. We examined the clinical features and molecular basis of hepatocyte nuclear factor-1α (HNF-1α) diabetes. Methods. Thirty-seven Japanese subjects with early onset Type II (non-insulin-dependent) diabetes mellitus and 45 with Type I (insulin-dependent) diabetes mellitus were screened for mutations in this gene. Functional properties of mutant HNF-1α were also investigated. Results. Three new mutations [G415R, R272C and A site of the promoter ( + 102G-to-C)] were found. Insulin secretion was impaired in the three subjects. Insulin and glucagon secretory responses to arginine in the subject with the R272C mutation were also diminished. Molecular biological studies indicated that the G415R mutation generated a protein with about 50 % of the activity of wild-type HNF-1α. The R272C mutation had no transactivating or DNA binding activity and acted in a dominant negative manner. The + 102 G-to-C mutation in the A site of the promoter activity was associated with an increase in promoter activity and it had 42–75 % more activity than the wild-type sequence. Conclusion/interpretation. Mutations in the HNF-1α gene may affect the normal islet function by different molecular mechanisms. [Diabetologia (1999) 42: 621–626]
    Type of Medium: Electronic Resource
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  • 9
    Electronic Resource
    Electronic Resource
    Springer
    Anatomy and embryology 199 (1999), S. 519-527 
    ISSN: 1432-0568
    Keywords: Key words Morphology ; Embryo culture ; Lipid droplet ; Development
    Source: Springer Online Journal Archives 1860-2000
    Topics: Medicine
    Notes: Abstract  The ultrastructure of bovine morulae and blastocysts developed from in vitro-matured and -fertilized oocytes in a serum-supplemented medium was compared with that of morulae and blastocysts collected non-surgically from superovulated cows. In the in vivo-derived morulae, two characteristic cells types could be identified by the electron-density of their cytoplasm and by their ultrastructural features. One type appeared light in color with low electron-dense cytoplasm. These cells were located in the peripheral layer of the cluster of blastomeres, possessed numerous cellular organelles such as mitochondria and Golgi apparatus and had microvilli projecting into the perivitelline space. The other cell type was distinguished by cytoplasm that stained more densely than that of the lighter-appearing cells. The darker-appearing cells generally possessed fewer organelles than the lighter cells, but many lysosome-like structures were present in the cytoplasm. The in vitro-developed morulae also contained two types of cells similar to those observed in the in vivo morulae. However, most of the in vitro-developed cells possessed numerous lipid droplets and contained fewer lysosome-like structures than the cells of the in vivo-derived morulae. The blastocysts, both in vivo and in vitro, showed a clear differentiation of trophoblast cells and inner cell mass (ICM)-cells. In the in vivo-derived blastocyst, the apical membrane of trophoblast cells was covered with large, numerous microvilli and well-developed junctional complexes were observed. Lipid droplets were present in the cytoplasm of trophoblast and ICM-cells but were not abundant. In vitro-developed blastocysts showed less well-developed junctional complexes between trophoblast cells, less well-developed apical microvilli on the trophoblast cells, and contained large numbers of lipid droplets. This accumulation of lipid droplets was higher in the trophoblast cells than in the ICM-cells. The zonae pellucidae of in vitro-developed embryos were thinner than that of the in vivo-derived embryos. This study demonstrates conspicuous differences in the ultrastructural features between the in vivo-derived and in vitro-developed embryos, suggesting that the ultrastructure may reflect the various physiological anomalies observed in previous studies.
    Type of Medium: Electronic Resource
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  • 10
    Electronic Resource
    Electronic Resource
    Springer
    The journal of membrane biology 152 (1996), S. 235-243 
    ISSN: 1432-1424
    Keywords: Key words: Na:K pump — Dopamine — Parathyroid hormone — Phospholipase C — Protein kinase C — Cytochrome P450-monooxygenase
    Source: Springer Online Journal Archives 1860-2000
    Topics: Biology , Chemistry and Pharmacology
    Notes: Abstract. To evaluate further the signal transduction mechanisms involved in the short-term modulation of Na-K-ATPase activity in the mammalian kidney, we examined the role of phospholipase C-protein kinase C (PLC-PKC) pathway and of various eicosanoids in this process, using microdissected rat proximal convoluted tubules. Dopamine (DA) and parathyroid hormone (either synthetic PTH1-34 or PTH3-34) inhibited Na-K-ATPase activity in dose-dependent manner; this effect was reproduced by PKC530-558 fragment and blocked by the specific PKC inhibitor calphostin C, as well as by the PLC inhibitors neomycin and U-73122. Pump inhibition by DA, PTH, or arachidonic acid, and by PKC activators phorbol dibutyrate (PDBu) or dioctanoyl glycerol (DiC8) was abolished by ethoxyresorufin, an inhibitor of the cytochrome P450-dependent monooxygenase pathway, but was unaffected by indomethacin or nordihydroguaiaretic acid, inhibitors of the cyclooxygenase and lipoxygenase pathways of the arachidonic acid cascade, respectively. Furthermore, each of the three monooxygenase products tested (20-HETE, 12(R)-HETE, or 11,12-DHT) caused a dose-dependent inhibition of the pump. The effect of DA, PTH, PDBu or DiC8, as well as that of 20-HETE was not altered when sodium entry was blocked with the amiloride analog ethylisopropyl amiloride or increased with nystatin. We conclude that short-term regulation of proximal tubule Na-K-ATPase activity by dopamine and parathyroid hormone occurs via the PLC-PKC signal transduction pathway and is mediated by cytochrome P450-dependent monooxygenase products of arachidonic acid metabolism, which may interact with the pump rather than alter sodium access to it.
    Type of Medium: Electronic Resource
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