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In vivo inhibition of phospholipaseA 2 in rat lung by an β-adrenergic agonist

  • Histamine and Immunology
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Abstract

Phospholipase A2 is the key enzyme for the release of arachidonic acid derived mediators via cycloxygenase or lipoxygenase pathways in inflammation and immunological processes. Activity of microsomal phospholipase A2 in rat lung can be inhibited byin vivo application of the ß-adrenergic drug fenoterol both in control and diseased animals.

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Authors and Affiliations

  1. Medizinische Poliklinik der Philipps-Universität Marburg, Emil Mannkopffstr. 1, D-3550, Marburg/Lahn, Federal Republic of Germany

    P. v. Wichert & W. Meyer

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  1. P. v. Wichert
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  2. W. Meyer
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v. Wichert, P., Meyer, W. In vivo inhibition of phospholipaseA 2 in rat lung by an β-adrenergic agonist. Agents and Actions 13, 233–234 (1983). https://doi.org/10.1007/BF01967339

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