Skip to main content
SpringerLink
Log in

Induction of osteoarthritis in guinea pigs by transection of the anterior cruciate ligament: Radiographic and histopathological changes

  • I. Cartilage degradation and osteoarthritis
  • Published:
Inflammation Research Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Altman RD, Dean DD. Osteoarthritis research: animal models. Seminars in Arthritis and Rheumatism 1990;19:21–5.

    PubMed  Google Scholar 

  2. Schwartz ER. Animal models: a means to study the pathogenesis of osteoarthritis. J Rheumatol 1987;14:101–3.

    PubMed  Google Scholar 

  3. Moskowitz RW, Davis W, Sammarco J, Martens M, Baker J, Mayor M, et al. Experimentally-induced degenerative joint lesions following partial menisectomy in the rabbit. Arthr Rheum 1973;16:397–405.

    Google Scholar 

  4. Meacock SC, Bodmer JL, Billingham ME. Experimental osteoarthritis in guinea pigs. J. Exper Pathol 1990;71(2):279–93.

    Google Scholar 

  5. Brandt KD, Myers SL, Burr D, Albrecht M. Osteoarthritic changes in canine articular cartilage, subchondral bone, and synovium fifty-four months after transection of the anterior cruciate ligament. Arthr Rheum 1991;34(12):1560–70.

    Google Scholar 

  6. Layton MW, Goldstein SA, Goulet RW, Feldkamp LA, Kubinski DJ, Bole GG. Examination of subchondral bone architecture in experimental osteoarthritis by microscopic computer axial tomography. Arthr Rheum 1988;31:1400–5.

    Google Scholar 

  7. Mankin HJ. Biochemical and Metabolic Aspects of Osteoarthritis. Orth Clin North America 1971;2:19–30.

    Google Scholar 

  8. Bendele AM, Hulman JF. Spontaneous cartilage degeneration in guinea pigs. Arthr Rheum 1988;31:561–5.

    Google Scholar 

Download references

Author information

Authors and Affiliations

  1. OsteoArthritis Sciences Inc., One Kendall Square, Building 200, 02139, Cambridge, MA, USA

    P. A. Jimenez, P. M. Harlan, A. E. Chavarria & H. B. Haimes

Authors
  1. P. A. Jimenez
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. P. M. Harlan
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. A. E. Chavarria
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. H. B. Haimes
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Jimenez, P.A., Harlan, P.M., Chavarria, A.E. et al. Induction of osteoarthritis in guinea pigs by transection of the anterior cruciate ligament: Radiographic and histopathological changes. Inflamm Res 44 (Suppl 2), S129–S130 (1995). https://doi.org/10.1007/BF01778296

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF01778296

Keywords

Search

Navigation