Abstract
The effect of synthetic salmon calcitonin was studied on adjuvant arthritis, pertussis vaccine edema, tuberculin skin reaction, passive direct Arthus reaction and nystatin edema. The results show that calcitonin inhibits these inflammatory processes.
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References
G. Milhaud andM.S. Moukhtar,Thyrocalcitonin: Effects on Calcium Kinetics in the Rat, Proc. Soc. Exp. Biol. Med.123, 207 (1966).
P.F. Hirsh, A. Shiwoski, H. Orimo, L. Dorago, R. Mewborn,On the Mode of the Hypocalcemie Action of Thyrocalcitonin and its Enhancement by Phosphate in Rats, Endocrinology93, 12 (1973).
J. Friedman andL.G. Raisz,Thyrocalcitonin: Inhibitor of Bone Resorption in Tissue Culture, Science150, 1465 (1965).
D.N. Kalu andG.V. Foster,Effect of Calcitonin on 3 H Proline Incorporation into Bone Hydroxyproline in the Rat, J. Endocrinol.49, 233 (1971).
A.W. Wase, J. Solewki, E. Riches andJ. Seidenberg,Action of Thyrocalcitonin on Bone, Nature214, 388 (1967).
O.L.M. Bijovet, J. Van der Sluys Veer andA.P. Jansen,Effects of Calcitonin on Patients with Paget's Disease, Thyrotoxicosis, or Hypercalcaemia, Lancet1, 876 (1968).
S. Wallach, J. Aloga andS. Cohn,Treatment of Osteoporosis with Calcitonin, Semin. Drug Treat.2, 21 (1972).
L. Riesterer andR. Jaques,Reduction of Increased Vascular Permeability by Calcitonin, Pharmacology3, 53 (1969).
S.E. Abdullahi, G. De Bastiani, L. Nogarin andG.P. Velo,Effect of Calcitonin on Carrageenan Foot Oedema, Agents and Actions5 (4), 371 (1975).
G.P. Velo, G. De Bastiani, L. Nogarin andS.E. Abdullahi,Anti-Inflammatory Effect of Calcitonin, in:Future Trends in Inflammation II (Eds. J.P. Giroud, D.A. Willoughby and G.P. Velo; Birkhäuser Verlag, Basel and Stuttgart, 1975), p. 284.
G.R. Bobalik, J.P. Aldred, R.R. Kleszynski, R.U. Stubbs, R.A. Zeedyk andJ.W. Bastian,Effects of Salmon Calcitonin and Combination Drug Therapy on Rat Adjuvant Arthritis, Agents and Actions4 (5), 364 (1974).
E. Arrigoni-Martelli, E. Bramm, E.C. Huskisson, D.A. Willoughby andP.A. Dieppe,Pertussis Vaccine Oedema: An Experimental Model for the Action of Penicillamine-Like Drugs. Agents and Actions6 (5), 613 (1976).
H. Megel, A. Raychandhuri, I. Shermano, T.H. Beaver andL.L. Thomas,The Anti-Inflammatory Actions of Tirolone Hydrochloride, Proc. Soc. Exp. Biol. Med.149, 89 (1975).
E. Arrigoni-Martelli, P. Schiatti andD. Selva,The Influence of Anti-Inflammatory and Immunosuppressant Drugs on Nystatin Induced Oedema, Pharmacology5, 215 (1971).
C.G. Cochrane andF.J. Dixon, in:Textbook of Immunopathology, vol. 1 (Eds. P.A. Miescher and H.J. Müller-Eberhard; Grune-Stratton, New York, 1968), p. 94.
J.P. Aldred, R.R. Kleszynski andJ.W. Bastian,Effects of Acute Administration of Porcine and Salmon Calcitonin on Urine Electrolyte Excretion in Rats, Proc. Soc. Exp. Biol. Med.134, 1175 (1970).
W. Braun andM. Ishizuka,Suppression and Enhancement of Antibody Formation by Alteration of Ca 2+ Levels, Nature226, 945 (1970).
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Abdullahi, S.E., Arrigoni Martelli, E., Bramm, E. et al. Effect of calcitonin on different inflammatory models. Agents and Actions 7, 533–538 (1977). https://doi.org/10.1007/BF02111126
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DOI: https://doi.org/10.1007/BF02111126