Conclusion
These studies on isolated intact mast cell granules, indicate that changes in the concentration of the divalent cations (Ca2+, Mg2+)alone cannot explain the membrane fusions and histamine release during sequential exocytosis in mast cells.
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Anderson, P., Röhlich, P. & Uvnäs, B. The effects of calcium on morphology and histamine content in isolated intact mast cell granules. Agents and Actions 8, 381 (1978). https://doi.org/10.1007/BF01968621
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DOI: https://doi.org/10.1007/BF01968621