Summary
Application of ACh on the isolated perfused retina of the frog elicited spikes of the optic nerve. The extent of this spike activity depended on the amount of ACh applied. The retinal response to ACh was varied by prostigmine and atropine as expected by their pharmacological properties. From these experiments it cannot be concluded that ACh is acting on the synapses of the firing ganglion cells directly.
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Trifonow, J., Ostrowski, M.A. & Dettmar, P. Impulsantworten des Nervus opticus auf Reizung der Netzhaut mit Acetylcholin. Experientia 25, 370–371 (1969). https://doi.org/10.1007/BF01899924
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DOI: https://doi.org/10.1007/BF01899924