Summary
A Golgi-rich fraction from rat liver has been shown to synthesize phosphatidylethanolamine from CDP-ethanolamine in vitro. The implications of the existence of such a pathway for the membrane flow hypothesis are discussed.
Similar content being viewed by others
References
G. F. Wilgram and E. P. Kennedy, J. biol. Chem.238, 2615 (1963).
L. M. G. Van Golde, B. Fleischer and S. Fleischer, Biochim. biophys. Acta249, 318 (1971).
L. M. G. Van Golde, J. Raben, J. J. Batenburg, B. Fleischer, F. Zambrano and S. Fleischer, Biochim. biophys. Acta360, 179 (1974).
W. C. McMurray and R. M. C. Dawson, Biochem. J.112, 91 (1969).
G. Dallner, in: Methods in Enzymology. Ed. S. P. Colowick and N. O. Kaplan. Academic Press, New York 1974.
J. M. Sturgess, E. Katona and M. A. Moscarello, J. Memb. Biol.12, 367 (1973).
T. K. Ray, Biochim. biophys. Acta196, 1 (1970).
G. Bligh and W. J. Dyer, Can. J. Biochem. Physiol.37, 911 (1959).
O. H. Lowry, N. J. Rosebrough, A. L. Farr and R. J. Randall, J. biol. Chem.193, 265 (1951).
D. J. Morré, T. W. Keenan and C. M. Huang, in: Advances in Cytopharmacology, vol. 2, p. 107. Ed. B. Ceccarelli, F. Clementi and J. Meldolesi. Raven Press, New York 1974.
Author information
Authors and Affiliations
Additional information
Acknowledgments. This study was supported by the Medical Research Council of Canada.
Rights and permissions
About this article
Cite this article
Chang, P.L., Sturgess, J.M. & Moscarello, M.A. Biosynthesis of phosphatidylethanolamine from CDP-ethanolamine by the Golgi complex of rat liver in vitro. Experientia 33, 1136–1137 (1977). https://doi.org/10.1007/BF01922285
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF01922285