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Thermoregulatory effects on the sheep of intracerebroventricular injections of L-glutamic acid

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Summary

L-glutamic acid injected in doses of 200–1000 nmoles·kg−1 into the cerebral ventricles of sheep had dose-dependent thermoregulatory effects: an increase in heat production and/or a decrease in respiratory frequency, and a rise in rectal temperature. A dose of 800 nmoles·kg−1 had effects comparable with those of a similar injection of 3 nmoles·kg−1 carbamylcholine.

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We wish to thank Miss Jill Thexton for invaluable assistance.

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Bligh, J., Silver, A., Bacon, M. et al. Thermoregulatory effects on the sheep of intracerebroventricular injections of L-glutamic acid. Experientia 34, 370–371 (1978). https://doi.org/10.1007/BF01923041

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  • DOI: https://doi.org/10.1007/BF01923041

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