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The pharmacological relevance of vital staining with neutral red

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Summary

The uptake of neutral red into the renin-containing juxtaglomerular granules does not inhibit the release of renin either in basal or in stimulated states of renin secretion. The vasodilating effect of neutral red may be due to a non-specific binding to noradrenaline-receptors in the vascular smooth muscle cells.

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Author notes

  1. Z. Nemes & S. Gomba

    Present address: Department of Pathology, University Medical School Debrecen, H-4012, Debrecen, Hungary

Authors and Affiliations

  1. Department of Pharmacology, University of Heidelberg, Im Neuenheimer Feld 366, D-6900, Heidelberg, (Federal Republic of Germany)

    Z. Nemes, R. Dietz, J. B. Lüth, S. Gomba, E. Hackenthal & F. Gross

Authors
  1. Z. Nemes
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  2. R. Dietz
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  3. J. B. Lüth
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  4. S. Gomba
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  5. E. Hackenthal
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  6. F. Gross
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Additional information

This work was supported by the German Research Foundation within the SFB 90 ‘Cardiovasculäres System’.

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Nemes, Z., Dietz, R., Lüth, J.B. et al. The pharmacological relevance of vital staining with neutral red. Experientia 35, 1475–1476 (1979). https://doi.org/10.1007/BF01962793

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  • DOI: https://doi.org/10.1007/BF01962793

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