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Changes in molecular species of pepsinogens in the development of the chick

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Summary

The potential peptic activity of the chick forestomach increases rapidly at the time of hatching. Together with this, the electrophoretic pattern of the pepsinogens shifts to the adult type. These changes take place even under the complete starvation of a newly hatched chick.

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Authors and Affiliations

  1. Zoological Institute, Faculty of Science, University of Tokyo, Bunkyo-ku, 113, Tokyo, Japan

    S. Yasugi, T. Mizuno & H. Esumi

  2. Biochemistry Division, National Cancer Center Research Institute, Chuo-ku, 104, Tokyo, Japan

    S. Yasugi, T. Mizuno & H. Esumi

Authors
  1. S. Yasugi
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  2. T. Mizuno
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  3. H. Esumi
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Additional information

We thank Dr A. Glucksmann, Cambridge, for reading the manuscript and helpful discussion, and Dr T. Sugimura, National Cancer Center, Tokyo, for his interest in our work. This work was supported by Grants-in-Aid for Cancer Research from the Ministry of Education, Science and Culture, Japan, and by Grant from the Toray Science Foundation.

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Yasugi, S., Mizuno, T. & Esumi, H. Changes in molecular species of pepsinogens in the development of the chick. Experientia 35, 814–815 (1979). https://doi.org/10.1007/BF01968268

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  • DOI: https://doi.org/10.1007/BF01968268

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