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Trimethoprim enhances the antibacterial activity of nalidixic and oxolinic acids and delays the emergence of resistance

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Summary

Trimethoprim enhances the in vitro activity of nalidixic and oxolinic acids against some representative pathogenic microorganisms, including those which are most frequently responsible for urinary tract infections, and delays the emergence of resistance in many of them.

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Authors and Affiliations

  1. Institute of Pharmacology, University of Modena, Via G. Campi 287, I-41100, Modena, Italy

    A. Bertolini, M. Castelli, Susanna Genedani & M. Garuti

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  1. A. Bertolini
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  2. M. Castelli
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  3. Susanna Genedani
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  4. M. Garuti
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Bertolini, A., Castelli, M., Genedani, S. et al. Trimethoprim enhances the antibacterial activity of nalidixic and oxolinic acids and delays the emergence of resistance. Experientia 36, 243–244 (1980). https://doi.org/10.1007/BF01953757

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  • DOI: https://doi.org/10.1007/BF01953757

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