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Stimulation of glycoprotein secretion in dispersed rat submandibular gland acini by cystic fibrosis serum

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Summary

Acini were enzymatically dissociated from rat submandibular gland and their mucous glycoproteins radiolabelled with14C-glucosamine. Sera from cystic fibrosis patients stimulated the release of labelled TCA/PTA — insoluble material from the cultured acinar cells to a significantly higher degree than did control sera.

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Authors and Affiliations

  1. Department of Pathology, The Research Institute, The Hospital for Sick Children, 555 University Avenue, M5G IX8, Toronto, Ontario, Canada

    N. Fleming & Jennifer M. Sturgess

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  1. N. Fleming
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  2. Jennifer M. Sturgess
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Additional information

This work was supported by the Canadian Cystic Fibrosis Foundation and the Sellers Foundation.

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Fleming, N., Sturgess, J.M. Stimulation of glycoprotein secretion in dispersed rat submandibular gland acini by cystic fibrosis serum. Experientia 37, 139–141 (1981). https://doi.org/10.1007/BF01963195

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  • DOI: https://doi.org/10.1007/BF01963195

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