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Inhibition of hypothalamic GnRH synthesis by inhibin

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Summary

Both testicular and ovarian inhibin preparations blocked GnRH synthesis by the hypothalamus and consequently reduced the circulating level of FSH. The serum level of LH was unaffected.

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Authors and Affiliations

  1. Institute for Research in Reproduction, Parel, 400 012, Bombay, India

    S. B. Moodbidri, S. Vijayalakshmi, A. H. Bandivdekar & A. R. Sheth

Authors
  1. S. B. Moodbidri
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  2. S. Vijayalakshmi
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  3. A. H. Bandivdekar
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  4. A. R. Sheth
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Additional information

Acknowledgment. We thank Dr S. Raiti of NIAMDD, National Institutes of Health, Bethesda, USA, for rat-hormone assay kits and Ms Maria Enrica Mongardi of Instituto Farmacologico Serono, Italy, for GnRH RIA kit.

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Moodbidri, S.B., Vijayalakshmi, S., Bandivdekar, A.H. et al. Inhibition of hypothalamic GnRH synthesis by inhibin. Experientia 37, 525–526 (1981). https://doi.org/10.1007/BF01986177

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  • DOI: https://doi.org/10.1007/BF01986177

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