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Common antigenicity between a human thymic epithelial cell product and a thymus-dependent serum factor

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  • Haematologica, Immunologica
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Summary

Specific immunofluorescence of human thymic epithelial cytoplasm was obtained with antibodies to supernatant of thymic epithelial cultures, and with anti-prealbumin antibodies. These antibodies also reacted with normal serum but not with serum from Di George patients. The data indicates that thymic epithelium and a component of the prealbumin fraction of normal serum share a common antigen believed to be thymic hormone.

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Authors and Affiliations

  1. Immunology Research Center, Armand-Frappier Institute, P.O. Box 100, H7N 4Z3, Laval, Québec, Canada

    E. F. Potworowski, Danuta Kowalczyk, V. V. Micusan & T. Seemayer

  2. Department of Pathology, Montreal Children's Hospital, Montreal, Canada

    E. F. Potworowski, Danuta Kowalczyk, V. V. Micusan & T. Seemayer

Authors
  1. E. F. Potworowski
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  2. Danuta Kowalczyk
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  3. V. V. Micusan
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  4. T. Seemayer
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Additional information

Acknowledgment. The authors wish to thank Mrs Francine Rivard and Claire Prévost for technical assistance and Dr A.R.C. Dobell for human thymic material. This work was supported by the National Cancer Institute of Canada and the Medical Research Council of Canada.

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Potworowski, E.F., Kowalczyk, D., Micusan, V.V. et al. Common antigenicity between a human thymic epithelial cell product and a thymus-dependent serum factor. Experientia 38, 859–860 (1982). https://doi.org/10.1007/BF01972317

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  • DOI: https://doi.org/10.1007/BF01972317

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