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The signal transducing system coupled to serotonin-S2 receptors

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  • The Platelet in Pathophysiological Research
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Summary

The signal transducing system coupled to the serotonin-S2 receptor on platelets involves metabolism of inositolcontaining phospholipid, elevation of intracellular free Ca2+ and activation of protein kinase C. Evidence for coupling of the serotonin-S2 receptor to the same signal transducing system in brain and smooth muscle tissue is reviewed.

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Authors and Affiliations

  1. Department of Biochemistry, Janssen Pharmaceutica Research Laboratories, B-2340, Beerse, Belgium

    D. de Chaffoy de Courcelles, J. E. Leysen & F. de Clerck

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  1. D. de Chaffoy de Courcelles
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  2. J. E. Leysen
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  3. F. de Clerck
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de Chaffoy de Courcelles, D., Leysen, J.E. & de Clerck, F. The signal transducing system coupled to serotonin-S2 receptors. Experientia 44, 131–133 (1988). https://doi.org/10.1007/BF01952195

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  • DOI: https://doi.org/10.1007/BF01952195

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