Skip to main content
Log in

Chemical reactions of 4,5,6,7-tetrahydro-4,5,7-trimethylpyrrolo[3,2-c]pyridine and its 2-formyl derivative

  • Published:
Chemistry of Heterocyclic Compounds Aims and scope

Abstract

N-Alkyl substituted tetrahydropyrrolo[3,2-c]pyridines have been obtained by alkylation of 4,5,6,7-tetrahydro-4,-5, 7-trimethylpyrrolo[3,2-c]pyridine and its 2-formyl derivative chloroalkyldimethylamines, acrylonitrile, methyl acetylenedicarboxylate and dichloroethane. 2-Formyl substituted tetrahydropyrrolo[3,2-c]pyridine has been reduced with sodium borohydride and condensed with monoethanolamine and hydroxylamine. The stereochemistry of the products has been studied by 1H NMR spectroscopy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. U.S.Pat. 3 992 544 (J. L. Archibald and K. Heatherington), C.A., 86, 140015 (1977).

    Google Scholar 

  2. T. N. Borisova, A. V. Varlamov, N. D. Sergeeva, A. T. Soldatenkov, V. P. Zvolinskii, A. A. Astakhov, and N. S. Prostakov, Khim. Geterotsikl. Soedin., No. 7, 973 (1987).

    Google Scholar 

  3. T. N. Borisova, A. V. Varlamov and N. S. Prostakov, Abstr. First All-Union Conference on the Chemistry, Biochemistry and Pharmacology of Indole Derivatives [in Russian], Tbilisi (1986), p. 39.

  4. T. N. Borisova, I. A. Stazharova, A. É. Aliev, N. S. Prostakov, and A. V. Varlamov, Khim. Geterotsikl. Soedin., No. 10, 1375 (1991).

    Google Scholar 

  5. A. É. Aliev, A. A. Sinitsyna, T. N. Borisova, I. A. Stazharova, N. S. Prostakov, and A. V. Varlamov, Khim. Geterotsikl. Soedin., No. 1, 75 (1993).

    Google Scholar 

  6. A. É. Aliev, Candidate of Chemical Science Thesis, Moscow (1988), p. 144.

  7. U. Burkert and N. Allinger, Molecular Mechanics [Russian translation], Mir, Moscow (1986), p. 364.

    Google Scholar 

  8. E. E. Stashenko, P. I. Zakharov, T. N. Borisova, B. S. Subbotin, and N. S. Prostakov, Khim. Geterotsikl. Soedin., No. 2, 212 (1988).

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Additional information

Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 5, pp. 681–687, May, 1993.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Varlamov, A.V., Borisova, T.N., Aliev, A.É. et al. Chemical reactions of 4,5,6,7-tetrahydro-4,5,7-trimethylpyrrolo[3,2-c]pyridine and its 2-formyl derivative. Chem Heterocycl Compd 29, 582–587 (1993). https://doi.org/10.1007/BF00534474

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF00534474

Keywords

Navigation