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Synthesis of derivatives of 1,2-diazabicyclo[2,2,2]octane. III

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Chemistry of Heterocyclic Compounds Aims and scope

Abstract

Synthesis of a number of 2-dialkylaminoalkyl-1, 2-diazabicyclo[2, 2, 2]octanes has been carried out starting from 1, 2-diazabicyclo[2, 2,2]-octane and passing through its 2-chloroacyl and 2-dialkylaminoacyl derivatives. It has been shown by means of NMR spectra that the methiodide of 2-methyl-1,2-diazabicyclo[2,2,2]octane has the structure of 1,2-dimethyl-2-aza-1-azoniabicyclo[2,2,2]octane iodide.

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References

  1. E. E. Mikhlina, N. A. Komarova, and M. V. Rubtsov, KhGS [Chemistry of Heterocyclic Compounds],2, 91, 1966.

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  2. E. E. Mikhlina, N. A. Komarova, and M. V. Rubtsov, KhGS [Chemistry of Heterocyclic Compounds],2, 259, 1966.

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For part II, see [2].

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Mikhlina, E.E., Turchin, K.F., Komarova, N.A. et al. Synthesis of derivatives of 1,2-diazabicyclo[2,2,2]octane. III. Chem Heterocycl Compd 5, 258–260 (1969). https://doi.org/10.1007/BF00943934

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  • DOI: https://doi.org/10.1007/BF00943934

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