Abstract
The condensation of cyanomethyl derivatives of furan and benzofuran with di- and trihydric phenols has given the corresponding 2,4-dihydroxy- and 2,4,6-trihydroxy-α-heterylacetophenones. The latter have been converted by reaction with acid anhydride, ethoxalyl chloride, and trifluoroacetic anhydride into 3-heterylchromones with methyl, trifluoromethyl, and ethoxycarbonyl groups in position 2.
Similar content being viewed by others
Literature cited
J. Harborne, The Biochemistry of Phenolic Compounds, Academic Press (1964).
V. P. Khilya, L. G. Grisnko, N. V. Sukharenko, and V. Sabo, Zh. Organ. Khim., 8, 1085 (1972).
V. P. Khilya, L. G. Grishko, L. L. Gontar', and V. Sabo, Khim. Geterotsikl. Soedin., 1324 (1972).
R. Fuson, J. Kneisley, and E. Kaiser, Org. Synth., 24, 33 (1944).
A. L. Mndzhoyan and A. A. Aroyan, Izv. Akad. Nauk ArmSSR, Ser. Khim., 14, 591 (1961).
R. Gaertner, J. Amer. Chem. Soc., 73, 4400 (1951).
E. Oregon, J. Amer. Chem. Soc., 74, 5319 (1952).
W. Baker, J. Chadderton, J. B. Harborne, and W. D. Ollis, J. Chem. Soc., 1852 (1953).
O. Moldenhaner, G. Trautmann, R. Pfluger, and H. Döser, Ann., 580, 182 (1953).
V. S. Dmitrieva, The Microbiological Control of the Activity of Antibiotic Agents [in Russian], Meditsina, Moscow (1965), p. 36.
N. S. Egorov, Principles of the Science of Antibiotics [in Russian], Moscow (1969), p. 138.
K. Nakanishi, Infrared Spectroscopy, Practical, Holden-Day (1962).
L. H. Briggs and L. D. Colebrook, J. Chem. Soc., 2458 (1960).
Author information
Authors and Affiliations
Additional information
Translated from Khimiya Geterotsiklicheskikh Soedinenii, No. 9, pp. 1202–1208, September, 1973.
Rights and permissions
About this article
Cite this article
Khilya, V.P., Grishko, L.G., Shevchenko, L.I. et al. Synthesis and properties of heterocyclic analogs of isoflavones. Chem Heterocycl Compd 9, 1091–1097 (1973). https://doi.org/10.1007/BF00474779
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF00474779