Summary
A description is given of the synthesis of the semicarbazone of diethyl 2-methylene-3-oxo-1,1-cyclo-pentanedicarboxylate; a study was made of its transformations, which permit the preparation of various sarkomycin analogs. Treatment of this semicarbazone with piperidine and dimethylamine gave the corresponding tertiary amines, which are of interest as starting materials for the synthesis of sarkomycin itself.
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Shemyakin, M.M., Ravdel, G.A., Chaman, E.S. et al. Sarkomycin and its analogs. Russ Chem Bull 8, 2073–2083 (1959). https://doi.org/10.1007/BF00909055
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DOI: https://doi.org/10.1007/BF00909055