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The new intrauterine contraceptive devices: Safe and effective

  • Published:
Advances in Contraception

Abstract

Reviews of the safety of intrauterine contraception usually are based on studies that do not reflect changes in clinical practice that have occurred over time, and that include many types of IUDs that are no longer used. Studies of insertions of the Multiload 375 and Copper T 380 performed since 1980, which more accurately reflect current clinical practice, show that these IUDs provide a high level of protection against pregnancy and are associated with low rates of complications. Current clinical opinion regarding the safety of IUDs needs to be reassessed in light of the positive safety record of these IUDs.

Resumé

Les études portant sur la sáreté de la contraception intra-utérine sont en général fondées sur des études ne reflètant pas les changements dans les pratiques cliniques intervenus au cours des années et se rapportent à de nombreux types de DIU qui ne sont plus utilisés. Les études concernant les insertions de Multiload 375 et Copper T 380 effectuées depuis 1980, qui d'ailleurs reflètent mieux la pratique clinique actuelle, indiquent que ces DIU offrent un haut niveau de protection contre les grossesses et qu'ils sont associés à de faibles pourcentages de complications. S'agissant de la sûreté des DIU, il y a lieu de réévaluer l'opinion clinique actuelle à la lumière des résultats positifs obtenus avec ces dispositifs dans ce domaine.

Resumen

Los estudios relativos a la seguridad de la anticoncepción intrauterina suelen basarse en estudios que no reflejan los cambios en las prácticas clínicas ocurridos con el correr del tiempo y que incluyen muchos tipos de DIU que ya no se utilizan. Los estudios relativos a las inserciones del Multiload 375 y Copper T 380 realizados después de 1980, y que reflejan mejor la práctica clínica actual, indican que estos DIU ofrecen un alto nivel de protección contra los embarazos y están asociados con bajos porcentajes de complicationes. En lo que respecta a la seguirdad de los DIU, es necesario evaluar nuevamente la opinión clínica actual a la luz de los resultados positivos obtenidos con estos dispositivos.

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References

  1. World Health Organization. Mechanism of action, safety, and efficacy of intrauterine devices. Technical Report Series 753. World Health Organization, 1987.

  2. Cates W, Grimes DA, Ory HW, Tyler CW. Publicity and the public health: the elimination of IUD-related abortion deaths. Fam Plann Perspect. 1977;9:138–40.

    Google Scholar 

  3. Pollack AE, Girvin S. When should an IUD be removed and replaced? Med Aspects Hum Sex. 1991;26(2):46–58.

    Google Scholar 

  4. Edelman DA, Berger GS, Keith L. The use of IUDs and their relationship to pelvic inflammatory disease: a review of epidemiologic and clinical studies. Curr Probl Obstet Gynecol. 1982;6(3):1–62.

    Google Scholar 

  5. Grimes DA. Intrauterine devices and pelvic inflammatory disease; recent developments. Contraception. 1987;36:97–109.

    Google Scholar 

  6. Timonen H, Nylander P, Kivijarvi A et al. Comparative performance of three copper IUDs (MLCu375, Fincoid, Nova-T) after one-year's follow-up in randomized multicenter trial. Contracept Deliv Syst. 1982;3(3/4): Abstract 226.

    Google Scholar 

  7. Thiery M, Van der Pas H, Van Kets H. The MLCu375 intrauterine contraceptive device. Adv Contracept. 1985;1:37–44.

    Google Scholar 

  8. Cole LP, Potts DM, Aranda C et al. An evaluation of the TCu 380Ag and the Multiload Cu375. Fertil Steril. 1985;43:214–7.

    Google Scholar 

  9. de Castro P, Perez-Inglesias R, Vicandi F et al. Comparison of two copper IUDs: the MLCu375 and the Nova-T. Adv Contracept. 1987;3:319–22.

    Google Scholar 

  10. Bratt H, Skjeldestad FG, Valentin KC. A randomized trial of three copper IUDs (MLCu250, MLCu375 and Nova T). Acta Obstet Gynecol Scand. 1988;67:247–51.

    Google Scholar 

  11. Lovset T. A comparative evaluation of the Multiload 250 and Multiload 375 intra-uterine devices. Acta Obstet Gynecol Scand. 1990;69:521–6.

    Google Scholar 

  12. Husain FA, Kazi A, Khan T. Clinical study of Multiload Cu375 in Pakistan. Adv Contracept. 1991;7:281–6.

    Google Scholar 

  13. Sastrawinata S, Farr G, Prihadi SM et al. A comparative clinical trial of the TCu 380A, Lippes Loop D and Multiload 375 IUDs in Indonesia. Contraception. 1991;44:141–54.

    Google Scholar 

  14. Ho J, Wu Z, Cai S et al. A randomized comparative trial of the MLCu375, TCu220C, Steel Ring and uterine Cavity-Shaped IUDs. Adv Contracept. 1992;8:161–6.

    Google Scholar 

  15. Cole LP, Potts DM, Aranda C et al. Comparative copper IUD trials. In: Zatuchni GI, Goldsmith A, Sciarra JJ, eds. Intrauterine Contraception: Advances and Future Prospects. Harper & Row. 1985:95–100.

  16. World Health Organization. The TCu380A, Multiload 250 and Nova T IUDs at 3, 5, and 7 years of use — results from three randomized multicentre trials. Contraception. 1990;42:141–58.

    Google Scholar 

  17. Sivin I, Mahgoub El S, McCarthy T et al. Long-term contraception with the levonorgestrel 20 μg/day (LNg 20) and Copper T 380Ag intrauterine devices: a five-year randomized study. Contraception. 1990;42:361–78.

    Google Scholar 

  18. Sivin I, Shaaban M, Odlind V et al. A randomized trial of the Gyne T 380 and Gyne T Slimline intrauterine copper devices. Contraception. 1990;42:379–89.

    Google Scholar 

  19. Norplant System. Physicians Desk Reference, 1992 ed. Medical Economics Data. Montvale, NJ. pp 2424–8.

  20. Saure A, Hirvonen E, Kivijarvi A, Timonen H. Comparative performance of Fincoid, Nova-T, ML 375 IUDs. In: Zatuchni GI, Goldsmith A, Sciarra JJ, eds. Intrauterine Contraception: Advances and Future Prospects. Harper & Row. 1985:104–8.

  21. Sung S, Qian L-J, Liu X. Two-year comparative clinical experience with three IUDs in China. In: Zatuchni GI, Goldsmith A, Sciarra JJ, eds. Intrauterine Contraception: Advances and Future Prospects. Harper & Row. 1985:109–14.

  22. Indian Council of Medical Research Task Force on IUD. Randomized clinical trial with intrauterine devices (levonorgestrel intrauterine device (LNG), CuT 380Ag, CuT 220C and CuT 200B). A 36-month study. Contraception. 1989;39:37–52.

    Google Scholar 

  23. Edelman DA, Berger GS, Keith L. Intrauterine devices and their complications. GK Hall & Co., 1979.

  24. Khomassuridze AG, Tsertsvadze GL, Kavkasidze GA. Two years of experience with the Multiload Cu375 in Georgia. Adv Contracept. 1991;7:287–90.

    Google Scholar 

  25. Wilson JC. A New Zealand randomized comparative study of three IUDs (Nova-T, MLCu375 and MLAgCu250): 1-, 2- and 3-year results. Adv Contracept. 1992;8:153–9.

    Google Scholar 

  26. Westrom L. Incidence, prevalence, and trends of acute pelvic inflammatory disease and its consequences in industrialized countries. Am J Obstet Gynecol. 1980;138:880–92.

    Google Scholar 

  27. Sandmire HF. Fertility after intrauterine device discontinuation. Adv Contracept. 1986;2:327–35.

    Google Scholar 

  28. Belhadj H, Sivin I, Diaz S et al. Recovery of fertility after, use of the levonorgestrel 20mcg/day or copper T 380 Ag intrauterine device. Contraception. 1986;34:261–7.

    Google Scholar 

  29. Skjeldestad EE, Bratt H. Return of fertility after use of IUDs (Nova T, MLCu250 and MLCu375). Adv Contracept. 1987;3:139–47.

    Google Scholar 

  30. Van Kets HE, Thiery M, Van der Pas H, Dieben TOM. Long-term experience with Multiload intrauterine devices. Adv Contracept. 1989;5:179–88.

    Google Scholar 

  31. Wilson JC. A prospective New Zealand study of fertility after removal of copper intrauterine contraceptive devices for conception and because of complications: a four-year study. Am J Obstet Gynecol. 1989;160:391–6.

    Google Scholar 

  32. Farley TM, Rosenberg MJ, Rowe PJ et al. Intrauterine devices and pelvic inflammatory disease: an international perspective. Lancet. 1992;339:785–7.

    Google Scholar 

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Authors and Affiliations

  1. Medical Research Consultants, 20 Bedford Ct., 07940, Madison, NJ, USA

    D. A. Edelman

  2. Victoria Women's Services, 86 Victoria Road, 28801, Asheville, NC, USA

    C. W. Porter Jr.

Authors
  1. D. A. Edelman
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  2. C. W. Porter Jr.
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Edelman, D.A., Porter, C.W. The new intrauterine contraceptive devices: Safe and effective. Adv Contracept 9, 83–91 (1993). https://doi.org/10.1007/BF02115905

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  • DOI: https://doi.org/10.1007/BF02115905

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