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Ferric reductases or flavin reductases?

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Abstract

Assimilation of iron by microorganisms requires the presence of ferric reductases which participate in the mobilization of iron from ferrisiderophores. The common structural and catalytic properties of these enzymes are described and shown to be identical to those of flavin reductases. This strongly suggests that, in general, the reduction of iron depends on reduced flavins provided by flavin reductases.

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Authors and Affiliations

  1. Laboratoire d'Etudes Dynamiques et Structurales de la Sélectivité, Unité de Recherche Associée au CNRS 332, Université Joseph Fourier, Grenoble, France

    Marc Fontecave, Jacques Covès & Jean-Louis Pierre

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  1. Marc Fontecave
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  2. Jacques Covès
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  3. Jean-Louis Pierre
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Fontecave, M., Covès, J. & Pierre, JL. Ferric reductases or flavin reductases?. Biometals 7, 3–8 (1994). https://doi.org/10.1007/BF00205187

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