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References

  1. Vermeulen NPE, Bessems JGM and Van de Straat R: Molecular aspects of paracetamol-induced hepatotoxicity and its mechanism-based prevention. Drug Metab. Rev.24, 367–407.

  2. Koymans L and Vermeulen NPE: “Active site structure of and mechanism of oxidation by cytochromes P450: a review” Drug Metab. Rev. In press.

  3. Vermeulen NPE, Donné-Op den Kelder and Commandeur JNM: Formation of and protection against toxic reactive intermediates. In: B. Testa, E. Kyburz, W Fuhrer and R. Giger (Eds),Proceedings XIIth international Symposium in Medical Chemistry, Basel, 13–18 September 1992, Verlag Helvetica Chimica Acta, Basel, and Verlag Chemie. Weinheim.

    Google Scholar 

  4. Van de Straat et al. (1986) Biochem. Pharmacol. 35:3693–3699

    PubMed  Google Scholar 

  5. P.M. Caldirola, H. van der Goot and H. Timmerman. Eur. J. Med. Chem, in press.

  6. Jandke, J. and Spiteller, G. (1987) J. Chromatogr. 421, 1–8.

    PubMed  Google Scholar 

  7. Sanduja, R., Ansari, G. A. S., and Boor, P. J. (1989) J. Appl. Toxicol.9, 235–238.

    PubMed  Google Scholar 

  8. J. Ch. Eriks et al., J. Med. Chem., 35 (1992) 3239.

    PubMed  Google Scholar 

  9. H. Weinstein et al., Mol. Pharmacol., 12 (1976) 738.

    PubMed  Google Scholar 

  10. D. M. Blow et al., Nature, 221 (1969) 337.

    PubMed  Google Scholar 

  11. C. L. Cooper et al., J. Biol. Chem., 264 (1989) 6202.

    PubMed  Google Scholar 

  12. M. J. A. Van Veldhuizen et al. Neurosci. Lett. 119 (1990) 233.

    PubMed  Google Scholar 

  13. Vree TB et al. Biopharm Drug Dispos 1992;13:445–60

    PubMed  Google Scholar 

  14. Vree TB et al. Pharm Weekbl [Sci] 1991;13:198–206

    Google Scholar 

  15. Vree TB et al. Pharm Weekbl [Sci] 1992;14:83–7.

    Google Scholar 

  16. Vree TB et al. J Chromatogr Biomed Appl 1992;578:239–49.

    Google Scholar 

Download references

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Authors and Affiliations

  1. Department of Pharmacochemistry, Vrijc Universiteit, De Boelelaan 1083, 1081, HV Amsterdam, The Netherlands

    Nico P. E. Vermeulen., G. M. Donné-Op den Kelder & Jan N. M. Commandeur

  2. AKZO-Pharma Division, Organon International B.V., P.O. Box 20, 5340, BH Oss, The Netherlands

    F. M. Kaspcrsen

  3. Division of Molecular Toxicology, Department of Pharmacochemistry, Faculty of Chemistry, Free University, De Boelelaan 1083, 1081, HV Amsterdam

    Jos G. M. Bessems, Johan M. te Koppele, Patricia A. van Dijk & Nico P. E. Vermeulen

  4. •TNO-IVVO, P O Box 430, 2300, AK Leiden, The Netherlands

    Johan M. te Koppele

  5. Division of Molecular Toxicology, Department of Pharmacochemistry, Vrije Universiteit, De Boelelaan 1083, 1081, HV Amsterdam, The Netherlands

    Jan N. M. Commandeur, Jan P. G. Brakenhoff, Lars W. Wormhoudt & Ed J. Groot

  6. Department of Pharmacochemistry, Vrije Universiteit, De Boelelaan 1083, 1081, HV Amsterdam, The Netherlands

    P. Caldirola, G. J. Bijloo & H. Timmerman

  7. Institut für Lasermedizin, Heinrich-Heine Universität, Düsseldorf, Germany

    R. Mannhold

  8. Med.-und Pharm.-Chem. Abteilung, Forschungsinstitut Borstel, Parkallee 10, D-2061, Borstel, Germany

    E. Coats

  9. Fac. Chemistry, Dept. Pharmacochemistry, Vrije Universiteit, de Boelelaan 1083, 1081, HV Amsterdam, The Netherlands

    T. L. Ching, G. R. M. M. Haenen & A. Bast

  10. Department of Pharmacochemistry, Vrije Universiteit, De Boelelaan 1083, 1081, HV Amsterdam, The Netherlands

    J. A. M. Christiaans, A. D. Windhorst, P. M. Groenenberg & H. van der Goot

  11. Department of Pharmacochemistry, Vrije Universiteit, De Boelelaan 1083, 1081, HV Amsterdam, The Netherlands

    H. Timmerman, J. A. M. Christiaans, A. D. Windhorst, P. M. Groenenberg & H. van der Goot

  12. Department of Pharmacochcmistry, Free University, De Boelelaan 1083, 1081, HV Amsterdam, The Netherlands

    Jan N. M. Commandeur, Nico P. E. Vermeulen, Ben M. de Rooij & Désirée A. Rijksen

  13. Shell Internationale Petroleum Maatschappij, The Hague, The Netherlands

    Peter J. Boogaard & Nico J. van Sittert

  14. Dept. of Medicinal Chemistry, University Centre for Pharmacy, A. Deusinglaan 2, 9713, AW Groningen, The Netherlands

    W. J. Drijfhout, C. J. Grol & B. H. C. Westerink

  15. Department of Pharmacochemistry, Vrije Universiteit, De Boelelaan 1083, 1081, HV Amsterdam, The Netherlands

    H. Timmerman, H. van der Goot & J. Ch. Eriks

  16. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Utrecht University, PO Box 80082, 3508, TB Utrecht, The Netherlands

    M. J. E. Fischer, J. J. C. Paulussen, D. A. Horbach, E. P. W. Roelofsen, N. J. de Mol & L. H. M. Janssen

  17. Dept. Pharmacology, University of Limburg, PO Box 616, 6200, MD Maastricht, The Netherlands

    J. J. R. Hermans & H. H. W. Thijssen

  18. Dept. of Med. Chem., Univ. Centre for Pharmacy, A. Deusinglaan 2, 9713, AW Groningen, The Netherlands

    C. J. Grol & J. M. Jansen

  19. Dept. of Org. Pharm. Chem., Biomedical Centre, Uppsala University, Box 574, S-751 23, Uppsala, Sweden

    A. Karlén & U. Hacksell

  20. Section Pharmaceutical Chemistry. Faculty of Pharmacy, Utrecht University, P.O. Box 80082, 3508, TB Utrecht, The Netherlands

    N. J. de Mol, L. H. M. Janssen, M. Maliepaard & C. A. M. C. Sitters

  21. Department of Pharmacochemistry, Vrije Universiteit, De Boelelaan 1083, 1081, HV Amsterdam, The Netherlands

    H. Timmerman, H. van der Goot & W. M. P. B. Menge

  22. Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Utrecht University, PO Box 80082, 3508, TB Utrecht, The Netherlands

    M. J. E. Fischer, J. J. C. Paulussen, D. A. Horbach, E. P. W. Roelofsen, N. J. de Mol & L. H. M. Janssen

  23. Division of Medicinal Chemistry and Division of Toxicology, Center for Bio-Pharmaceutical Sciences, P.O.Box 9502, 2300, RA Leiden, The Netherlands

    A. M. van Rhee, E. C. A. van Winden, J. F. Nagelkerke, H. J. G. M. de Bont, A. P. Ijzerman & W. Soudijn

  24. Netherlands Institute for Brain Research, Meibergdreef 33, 1105, AZ Amsterdam ZO, The Netherlands

    M. J. A. Van Veldhuizen, M. G. P. Feenstra & G. J. Boer

  25. National Institute of Public Health and Environmental Protection, P.O. Box 1, 3720, BA Bilthoven, The Netherlands

    W. Vleeming, J. Riezebos, J. G. C. van Amsterdam, J. Wemer, D. J. de Wildt & A. J. Porsius

  26. Department of Farmcotherapy, Faculty of Pharmacy, University Utrecht, The Netherlands

    A. J. Porsius

  27. Department of Clinical Pharmacy, Academic Hospital Nijmegen Sint Radboud, P.O.Box 9101, 6500, HB Nijmegen, The Netherlands

    T. B. Vree, E. W. J. van Ewijk-Beneken Kolmer, M. van den Biggelaar-Martea, C. P. W. G. M. van Wissen-Verwey & M. M. M. Broekman

  28. Department of Pharmacochemistry, Vrije Universiteit, De Boelelaan 1083, 1081, HV Amsterdam

    P. Caldirola, H. Timmerman & M. Q. Zhang

  29. Department of Medicinal Chemistry II, Organon International B.V., 5340, BH Oss, The Netherlands

    D. C. Leysen

Authors
  1. Nico P. E. Vermeulen.
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  2. G. M. Donné-Op den Kelder
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  3. Jan N. M. Commandeur
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  4. F. M. Kaspcrsen
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  5. Jos G. M. Bessems
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  6. Johan M. te Koppele
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  7. Patricia A. van Dijk
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  8. Nico P. E. Vermeulen
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  9. Jan P. G. Brakenhoff
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  10. Lars W. Wormhoudt
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  11. Ed J. Groot
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  12. P. Caldirola
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  13. G. J. Bijloo
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  14. R. Mannhold
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  15. E. Coats
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  16. H. Timmerman
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  17. T. L. Ching
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  18. G. R. M. M. Haenen
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  19. A. Bast
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  28. W. J. Drijfhout
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  29. C. J. Grol
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  30. B. H. C. Westerink
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  31. J. Ch. Eriks
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  32. M. J. E. Fischer
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  33. J. J. C. Paulussen
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  34. D. A. Horbach
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  35. E. P. W. Roelofsen
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  36. N. J. de Mol
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  37. L. H. M. Janssen
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  43. M. Maliepaard
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  44. C. A. M. C. Sitters
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  47. E. C. A. van Winden
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  51. W. Soudijn
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  64. C. P. W. G. M. van Wissen-Verwey
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  65. M. M. M. Broekman
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  67. D. C. Leysen
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Financially supported by the Dutch Cancer Society

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Vermeulen., N.P.E., den Kelder, G.M.DO., Commandeur, J.N.M. et al. Abstracts of papers. Pharm World Sci 15, 3A–9A (1993). https://doi.org/10.1007/BF01884918

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