Abstract
The purpose of this research was to develop a quality of life (QOL) tool that would help to reveal any physical, mental or emotional changes patients may experience while receiving radiation therapy. Research focusing on quality of life during radiation therapy is in its infancy. Although many tools to measure QOL have been developed, until very recently few had been geared specifically toward those receiving radiation therapy. In addition to a radiation-specific instrument, the goal was to develop a multidimensional measure that would be short in length and could be completed by the patient in 15 min or less. This new Quality of Life Radiation Therapy Instrument (QOL_RTI) is a visual analogue scale with 24 questions and is not site specific. Twenty-one patients with varlous diagnoses and treatment sites completed the questionnalre at baseline and then weekly during the course of radiation therapy. The internal consistency of the instrument (Cronbach's alpha) was 0.87. At baseline each patient also was asked to complete the Ferran's and Powers QLI Cancer Version 6 (QLIC); the correlation between the QLIC and the QOL-RTI was 0.47. These results are based on a small number of patients, but initlal efforts in creating an instrument that is quick and easy for patients to complete have been encouraging. An additional 70–80 patients are now being entered into a study using the QOL-RTI to further evaluate reliabillty and validity.
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References
Donovan K, Snason-Fisher RW, Redman S. Measuring quality of life in cancer patients. J Clin Oncol 1989; 7: 959–968.
Cella DF, Tulsky DS. Measuring quality of life today: methodological aspects. Oncology 1990; 4: 29–38.
Gotay CC, Korn EL, McCabe MS, Moore TD, Cheson BD. Quality-of-life assessment in cancer treatment protocols: research issues in protocol development. JNCI 1992; 84: 575–579.
Grant M, Padilla GV, Ferrell BR, Rhiner M. Assessment of quality of life with a single instrument. Semin Oncol Nurs 1990; 6: 260–270.
Spilker B, White WSA, Rolly LS, Tilson HH. Quality of life bibliography and indexes. J Clin PharPharmacoepidemiol 1992; 6: 87–156.
Aaronson VK. Quality of life research in cancer clinical trials: A need for common rules and language. Oncology 1990; 4: 59–66.
Connil C, Verger E, Salamero M. Performance status assessment in cancer patients. Cancer 1990; 65: 1864–1866.
Karnofsky DA, Burchenal JH. The clinical evaluation of chemotherapeutic agents in cancer. In: Macleod CM (ed) Evaluation of Chemotherapeutic Agents. New York: Columbia University Press 1949: 199–205.
Schag CC, Heinrich RL, Ganz PA. Karnofsky Performance Status revisited: reliability, validity, and guidelines. J Clin Oncol 1984: 2: 187–193.
Schipper H, Clinch J, McMurray A, Levitt M. Measuring the quality of life of cancer patients: The Functional Living Index—Cancer: development and validation. J Clin Oncol 1984; 2: 472–483.
Cleary PD, Jette A. The validity of self-reported physician utilization measures. Med Care 1984; 22: 796–803.
Cella DF, Tulsky DS, Gray G et al. The Functional Assessment of Cancer Therapy Scale: development and validation of the general measure. J Clin Oncol 1993; 11: 570–579.
Bjordal K, Kaasa S. Psychometric validation of the EORTC core quality of life questionnaire, 30-item version and a diagnosis-specific module for head and neck cancer patients. Acta Oncol 1992; 31: 311–321.
Kahn SB, Houts PS, Harding SP. Quality of life and patients with cancer: a comparative study of patient versus physician perceptions and its implications for cancer education. J Cancer Educ 1992; 7: 241–249.
Slevin ML, Plant H, Lynch D, Drinkwater J, Gregory WM. Who should measure quality of life, the doctor or the patient. Br J Cancer 1988; 57: 109–112.
Ferrans CE. Quality of life: conceptual issues. Semin Oncol Nurs Prac 1990; 6: 255–259.
Tchekmedyian NS, Cella DF (eds). Quality of life in current oncology practice and research. Oncology 1990; 4(5): 209–232.
Ganz PA. Age and gender as factors in cancer therapy. Clin Geriatr Med 1993; 9: 145–155.
O'Young J, McPeek B. Quality of life variables in surgical trials. J Chronic Dis 1987; 40: 513–522.
Ganz PA, Lee JJ, Siau J. Quality of life assessment. An independent prognostic variable for survival in lung cancer. Cancer 1991; 67: 3131–3135.
Osoba D. The Quality of Life Committee of the Clinical Trials of the National Cancer Institute of Canada: organization and functions. Qual Life Res 1992; 1: 211–218.
Moinpour CM, Feigl P, Metch B, Hayden KA, Meyskens FL Jr, Crowley J. Quality of life end points in cancer clinical trials: review and recommendations. JNCI 1989; 81: 485–495.
Schipper H. Guidelines and caveats for quality of life measurement in clinical practice and research. Oncology 1990; 4: 51–57.
Ganz PA, Haskell CM, Figlin RA, et al. Estimating the quality of life in a clinical trial of patients with metastatic lung cancer using the Karnofsky Performance Status and the Functional Living Index-Cancer. Cancer 1988; 61: 849–856.
Hopwood P. Progress, problems and priorities in quality of life research. Eur J Cancer 1992; 28A: 1748–1752.
Padila GV, Grant MM, Lipsett J, Anderson PR, Rhiner M, Bogen C. Health quality of life and colorectal cancer. Cancer 1990; 70: 1450–1456.
Johnson JE, King KB, Murray RA. Measuring the impact of sickness on usual functions of radiation therapy patients. Oncol Nurs Forum 1983; 10: 36–39.
Varricchio CG. Relevance of quality of life to clinical nursing practice. Semin Oncol Nurs 1990; 6: 255–259.
Padilla GV. Validity of health-related quality of life subscales. Prog Cardiovasc Nurs 1992; 7: 13–20.
Sellitz C, Wrightsman L, Cook S. Research Methods in Social Relations. New York: Holt, Rinehart and Winston, 1976.
Ferrans CE, Powers MJ. Quality of Life Index. Development and psychometric properties. Adv Nurs Sci 1985; 8: 15–24.
Tulsky DS. An introduction to test theory. Oncology 1990; 4: 43–48; discussion 69–70.
Cronbach LJ. Coefficient alpha and the internal structure of tests. Psychometrica 1951; 16: 247–334.
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Previously published in abstract form: Qual Life Res 1994; 3: 82–83.
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Johnson, D.J., Casey, L. & Noriega, B. A pilot study of patient quality of life during radiation therapy treatment. Qual Life Res 3, 267–272 (1994). https://doi.org/10.1007/BF00434900
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DOI: https://doi.org/10.1007/BF00434900