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Expression of the human α-1-antitrypsin gene in heterologous mammalian cells

  • Experimental Genetics
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

A genetic-engineering construction is developed containing the full-size cDNA of human α-1-antitrypsin, controlled by the promotor and enhancer elements from cytomegalovirus. It is shown that, after transfection with this recombinant DNA, it is properly expressed in heterologous animal cells.

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Authors and Affiliations

  1. Research Institute of Experimental Medicine, Russian Academy of Medical Sciences, St. Petersburg

    N. B. Dolzhanskaya, A. L. Shvartsman & V. S. Gaitskhoki

Authors
  1. N. B. Dolzhanskaya
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  2. A. L. Shvartsman
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  3. V. S. Gaitskhoki
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, vol. 117, No 2, pp. 166–167, Feburary, 1993

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Dolzhanskaya, N.B., Shvartsman, A.L. & Gaitskhoki, V.S. Expression of the human α-1-antitrypsin gene in heterologous mammalian cells. Bull Exp Biol Med 117, 166–167 (1994). https://doi.org/10.1007/BF02444134

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  • DOI: https://doi.org/10.1007/BF02444134

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