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Effect of repeated complete starvation on quantitative parameters of rat cardiomyocytes

  • Morphology and Pathomorphology
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Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

Sixty-four male Wistar rats were subjected to repeated complete starvation with free access to water. Each starvation period lasted 6 days and was followed by a 7-day recovery period. The concentration of cardiomyocytes (CMC) and their total number in the left ventricle (LV) were measured after alkaline dissociation of the myocardium. The volume density of muscle fibers and their absolute total mass in the LV were determined by stereological analysis. It is shown that after 6 successive starvation periods the proliferative potential of the CMC population is reduced.

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Authors and Affiliations

  1. Institute of Regional Pathology and Pathological Morphology, Siberian Division of the Russian Academy of Medical Sciences, Novosibirsk

    L. M. Nepomnyashchikh, D. E. Semenov & V. G. Tsimmerman

Authors
  1. L. M. Nepomnyashchikh
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  2. D. E. Semenov
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  3. V. G. Tsimmerman
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Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 117, No 6, pp. 658–660, June, 1994

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Nepomnyashchikh, L.M., Semenov, D.E. & Tsimmerman, V.G. Effect of repeated complete starvation on quantitative parameters of rat cardiomyocytes. Bull Exp Biol Med 117, 665–668 (1994). https://doi.org/10.1007/BF02444350

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  • DOI: https://doi.org/10.1007/BF02444350

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