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Composition of glycoproteins of the supraepithelial mucous layer of the intestinal tract for administration of pentagastrin and carbacholine

  • Physiology
  • Published:
Bulletin of Experimental Biology and Medicine Aims and scope

Abstract

The composition of structural glycoproteins from the supraepithelial mucous layer of the stomach and intestine was determined by the concentration of the protein part and monosaccharides of the oligosaccharide part in dogs. It is shown that after administration of pentagastrin at 10 μg/kg and carbacholine at 6 μg/kg the release of structural glycoproteins increases in the stomach (the degree of glycosylation as well as the partial composition of monosaccharides does not markedly change). After stimulation of gastric secretion, the release of structural glycoproteins in the intestine increases insignificantly, whereas the glycosylation of glycoproteins from the supraepithelial mucous layer of the stomach is intensified.

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Authors and Affiliations

  1. Department of Normal Physiology, Siberian State Medical Univeristy, Tomsk

    M. A. Medvedev, N. A. Krivova, T. I. Selivanova & O. B. Zaeva

  2. Laboratory of Digestion Physiology, Research Institute of Biology and Biophysics, Tomsk State University, Tomsk, USSR

    M. A. Medvedev, N. A. Krivova, T. I. Selivanova & O. B. Zaeva

Authors
  1. M. A. Medvedev
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  2. N. A. Krivova
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  3. T. I. Selivanova
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  4. O. B. Zaeva
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Additional information

Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 118, No 9, 237–240, September, 1994

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Medvedev, M.A., Krivova, N.A., Selivanova, T.I. et al. Composition of glycoproteins of the supraepithelial mucous layer of the intestinal tract for administration of pentagastrin and carbacholine. Bull Exp Biol Med 118, 933–936 (1994). https://doi.org/10.1007/BF02445776

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  • DOI: https://doi.org/10.1007/BF02445776

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