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DNA polymorphisms in the ψβ1- and β-globin gene regions in asian macaques

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Abstract

DNA polymorphisms in the ψβ1-β-globin gene region in nine Asian macaques(Macaca fuscata, M. mulatta, M. nemestrina, M. cyclopis, M. fascicularis, M. arctoides, M. radiata, M. maura, andM. assamensis) were examined using several restriction endonucleases and the human ψβ1, δIVS2, and βIVS2 probes. TheBamHI site 3′ to the β-globin gene was polymorphic inM. fuscata andM. mulatta, while the HincII site and the EcoRI site in the ψβ1-globin gene region was highly polymorphic inM. fuscata andM. mulatta, respectively. These polymorphic sites also seem to be present in other Asian macaques. The present study of the polymorphism at theBamHI site 3′ to the β-globin gene in Asian macaques supports, at the nuclear DNA level, the idea that thefascicularis group includingM. fuscata, M. mulatta, M. cyclopis, andM. fascicularis is different from other Asian macaque groups.

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Authors and Affiliations

  1. Department of Morphology, Institute for Developmental Research, Aichi Prefectural Colony, 480-03, Kasugai, Aichi, Japan

    K. Shimizu

  2. Department of Biochemistry, Primate Research Institute, Kyoto University, 484, Inuyama, Aichi, Japan

    O. Takenaka

Authors
  1. K. Shimizu
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  2. O. Takenaka
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Additional information

This study was supported in part by the Cooperation Research Program of the Primate Research Institute, Kyoto University.

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Shimizu, K., Takenaka, O. DNA polymorphisms in the ψβ1- and β-globin gene regions in asian macaques. Biochem Genet 29, 177–187 (1991). https://doi.org/10.1007/BF02401811

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  • DOI: https://doi.org/10.1007/BF02401811

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