Skip to main content
SpringerLink
Log in

The effect of localized gastric hypothermia on gastric secretion in dogs

  • Published:
The American Journal of Digestive Diseases Aims and scope Submit manuscript

Summary

The effect of localized hypothermia on gastric secretion was studied in dogs with gastrostomies and vagally innervated and denervated pouches.

The output of acid of gastric pouches in response to various stimuli was reduced following gastric freezing. When the entire stomach, in contrast to a pouch, was frozen, significant depression in secretion of acid was not observed.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Wangensteen, O. H., Peter, E. T., Nicoloff, D. M., Walder, A. I., Sosin, H., andBernstein, E. F. Achieving “physiological gastrectomy” by gastric freezing: A preliminary report of an experimental and clinical study.JAMA 180:439, 1962.

    PubMed  Google Scholar 

  2. Peter, E. T., Bernstein, E. F., Sosin, H., Madsen, A. J., Walder, A. I., andWangensteen, O. H. Technique of gastric freezing in the treatment of duodenal ulcer.JAMA 181:760, 1962.

    PubMed  Google Scholar 

  3. Wangensteen, O. H., Peter, E. T., Bernstein, E. F., Walder, A. I., Sosin, H., andMadsen, A. J. Can physiological gastrectomy be achieved by gastric freezing?Ann Surg 156:579, 1962.

    PubMed  Google Scholar 

  4. Peter, E. T., Bernstein, E. F., Walder, A. I., Madsen, A. J., Sosin, H., andWangensteen, O. H. Effect of profound gastric hypothermia (gastric freezing) upon various phases of gastric secretion.Surg Forum 13:269, 1962.

    PubMed  Google Scholar 

  5. Gregory, R. A., andTracy, H. J. The preparation and properties of gastrin.J Physiol (Lond) 156:523, 1961.

    PubMed  Google Scholar 

  6. Barsoum, G. S., andGaddum, J. H. The pharmacological estimation of adenosine and histamine in blood.J Physiol (Lond) 85:1, 1935.

    Google Scholar 

  7. Bernstein, E. F., Goodale, R. L., Jr., McFee, A. S., Madsen, A. J., Delaney, J. P., andWangensteen, O. H. Interim report on results of gastric freezing for peptic ulcer: Present indications, limitations, and clinical achievement.JAMA 187: 436, 1964.

    PubMed  Google Scholar 

  8. Savage, L. E., Stavney, L. S., Stevenson, J. K., Harkins, H. N., andNyhus, L. M. Secretory studies in frozen Heidenhain pouches.Arch Surg 87:690, 1963.

    PubMed  Google Scholar 

  9. Meredith, J. H., Myers, R. T., andBradshaw, H. H. Acid secretion in stomach pouches made after freezing the stomach.Ann Surg 158:440, 1963.

    PubMed  Google Scholar 

  10. Berg, C. D., andNanson, E. M. Effects of gastric freezing on isolated denervated gastric pouch in dogs.Canad Med Ass J 90:1337, 1964.

    PubMed  Google Scholar 

  11. Gilat, T., Clapp, P., Sherlock, P., Creemers, J., Tayao, M. S., Lipkin, M., andAlmy, T. P. Effects of freezing on the gastric mucosa of dogs.Gastroenterology 46: 680, 1964.

    PubMed  Google Scholar 

  12. Berg, C. D., andNanson, E. M. Effects of gastric freezing on gastric secretions in dogs.Surg Forum 14: 352, 1963.

    PubMed  Google Scholar 

  13. Scott, H. W., Jr., Shull, H. J., O'Neill, J. A., Jr., andRichie, R. E. Experimental and clinical appraisal of gastric freezing for duodenal ulcer.Ann Surg 159:769, 1964.

    PubMed  Google Scholar 

  14. Fores, R. G., Mitchell, W. E., andWeldon, C. S. Duration of suppression of acid secretion in response to histamine stimulation following freezing of the canine stomach.Bull Hopkins Hosp 114:249, 1964.

    PubMed  Google Scholar 

  15. McIlrath, D. C, Hallenbeck, G. A., Allen, H. A., Mann, C. V., Baldes, E. J., Brown, A. L., Jr., andRovelstad, R. A. Gastric freezing: An experimental study.Gastroenterology 45:374, 1963.

    PubMed  Google Scholar 

  16. Hightower, N. C, Jr. Personal communication.

  17. McSweeney, E. D., Jr., Melnyk, C.S., Deshpande, P. J., Benson, J. A., Jr., andJacob, S. W. The supercooled stomach.Surg Forum 14:347, 1963.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. From the Sections of Surgical Research and Physiology, Mayo Clinic and Mayo Foundation, Rochester, Minn.

    Hubert A. Allen M.D., Charles V. Mann M.D., Donald C. McIlrath M.D., Charles F. Code M.D. & George A. Hallenbeck M.D.

  2. the Departments of Gastroenterology and Physiology, Mayo Graduate School of Medicine (University of Minnesota), Rochester, Minn.

    Hubert A. Allen M.D., Charles V. Mann M.D., Donald C. McIlrath M.D., Charles F. Code M.D. & George A. Hallenbeck M.D.

Authors
  1. Hubert A. Allen M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Charles V. Mann M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Donald C. McIlrath M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Charles F. Code M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. George A. Hallenbeck M.D.
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Supported in part by Research Grant A-5920 from the National Institutes of Health, U. S. Public Health Service.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Allen, H.A., Mann, C.V., McIlrath, D.C. et al. The effect of localized gastric hypothermia on gastric secretion in dogs. Digest Dis Sci 11, 702–709 (1966). https://doi.org/10.1007/BF02239423

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02239423

Keywords

Search

Navigation