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Cytology of the gastric mucosa in the development of chronic gastritis

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Abstract

Cellular changes were studied in specimens of the gastric mucosa from 131 patients with gastric biopsies from the normal mucosa and from those with various forms of chronic gastritis. The normal gastric mucosa was associated with moderate cell exfoliation and with normal cell structures. In cases of superficial gastritis and interstitial gastritis, the cellular material was more abundant than in smears from the normal stomach. The cells encountered were of surface mucosal and often also of glandular origin and were found together with numerous inflammatory cells. Cases with preatrophic and atrophic gastritis and with gastritis of the stomach remnant presented evidence of cellular metaplasia and nuclear and cytoplasmic alterations in surface mucosal cells. The results from study of gastric cellular changes in smears have led to further clarification of the diagnostic role of cytology which reflects the histologic alterations of gastric disorders and also often complements gastric biopsy findings.

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Cheli, R., Carli, C. & Ciancamerla, G. Cytology of the gastric mucosa in the development of chronic gastritis. Digest Dis Sci 19, 161–166 (1974). https://doi.org/10.1007/BF01072628

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