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The heterogeneity of IgA deficiency

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References

  1. Rockey JH, Hanson LÅ, Heremans JF, Kunkel HG: Beta-2A aglobulinemia in two healthy men. J Lab Clin Med 63:205–212, 1964

    Google Scholar 

  2. Amman AJ, Hong R: Disorders of the IgA system.In Immunologic Disorders in Infants and Children, 2nd ed, RT Stiehm, V Fulginiti (eds). Philadelphia, Saunders, 1980, pp 260–273

    Google Scholar 

  3. Hanson LÅ, Björkander J, Oxelius VA: Selective IgA deficiency.In Primary and Secondary Immunodeficiency Disorders, RK Chandra (ed). New York, Churchill-Livingstone, 1983, pp 62–84

    Google Scholar 

  4. Hanson LÅ, Brandtzaeg P: Mucosal defense.In Immunologic Disorders in Infants and Children, 2nd ed, RT Stiehm, V Fulginiti (eds). Philadelphia, Saunders, 1980, pp 137–164

    Google Scholar 

  5. Karlsson G, Petruson B, Björkander J, Hanson LÅ: Infections of the nose and paranasal sinuses in adult patients with immunodeficiency. Arch Otolaryngol 111:290–293, 1985

    Google Scholar 

  6. Björkander J, Bake B, Hanson LÅ: Primary hypogammaglobulinemia: Impaired lung function and body growth with delayed diagnosis and inadequate treatment. Eur J Resp Dis 65:529–536, 1984

    Google Scholar 

  7. Björkander J, Bengtson U, Oxelius VA, Hanson LÅ: Symptoms in patients with lowered levels of IgG subclasses, with or without IgA deficiency, and effects of immunoglobulin prophylaxis.In Immunoglobulin Subclass Deficiencies (Monogr Allergy ZO), LÅ Hanson, T Söderström, VA Oxelius (eds). Basel, Karger, 1986, pp 157–163

    Google Scholar 

  8. Björkander J, Bake B, Oxelius VA, Hanson LÅ: Impaired lung function in patients with IgA deficiency and low levels of IgG2 or IgG3. N Engl J Med 313:720–724, 1985

    Google Scholar 

  9. Brandtzaeg P, Fjellanger I, Gjeruldsen ST: Immunoglobulin M: Local synthesis and selective secretion in patients with immunoglobulin A deficiency. Science 160:789–791, 1968

    Google Scholar 

  10. Mellander L, Björkander J, Carlsson B, Hanson LÅ: Secretory antibodies in IgA deficient and immunosuppressed individuals. J Clin Immunol 6:284–291, 1986

    Google Scholar 

  11. Brandtzaeg P, Karlsson G, Hansson G, Petruson B, Björkander J, Hanson LÅ: The clinical condition of IgA-deficient patients is related to the proportion of IgD- and IgM-producing cells in their nasal mucosa. Clin Exp Immunol 67:626–636, 1987

    Google Scholar 

  12. Karlsson G, Hansson HA, Petruson B, Björkander J: The nasal mucosa in immunodeficiency. Surface morphology, mucociliary function and bacteriological findings in adult patients with variable immunodeficiency or selective IgA deficiency. Acta Otolaryngol (Stockh) 100:456–469, 1985

    Google Scholar 

  13. Karlsson G, Hansson HA, Petruson B, Björkander J, Hanson LÅ: Goblet cell number in the nasal mucosa relates to cell-mediated immunity in patients with antibody deficiency syndromes. Int Arch Allergy Appl Immunol 78:86–91, 1985

    Google Scholar 

  14. Hanson LÅ, Avanzini MA, Björkander J, McLeod Griffiss J, Robbins JB, Schneerson R, Söderström R, Söderström T: Results of vaccination in patients with IgA deficiency and/or IgG subclass deficiencies (in press)

  15. Savilahti E, Klemola T, Hovi T, Carlsson B, Stenvik M, Mellander L, Tiainen P: IgA deficient persons excrete attenuated vaccine viruses longer than controls.In Progress in Immunodeficiency Research and Therapy. J Vossen, C Griscelli (eds). Amsterdam, Excerpta Medica, 1986, Vol II, pp 261–267

    Google Scholar 

  16. Oxelius VA, Laurell AB, Lindquist B, Golebiowska H, Axelsson U, Björkander J, Hanson LÅ: IgG subclasses in selective IgA deficiency: Importance of IgG2-IgA deficiency. Engl J Med 304:1476–1477, 1981

    Google Scholar 

  17. Epstein LB, Amman R: Evaluation of T lymphocyte effector function in immunodeficiency diseases: Abnormality in mitogen stimulated interferon in patients with selective IgA deficiency. J Immunol 112:617–626, 1974

    Google Scholar 

  18. Strannegård Ö, Björkander J, Hellstrand K, Pacsa A, Hermodsson S, Hanson LÅ: Interferon and β2-microglobulin in patients with common variable immunodeficiency or selective IgA deficiency. Int Arch Allergy Appl Immunol 84:217–222, 1987

    Google Scholar 

  19. Strannegåard Ö, Björkander J, Hanson LÅ, Hermodsson S: Natural killer cells in common variable immunodeficiency and selective IgA deficiency. Clin Immunol Immunopathol 25:325–334, 1982

    Google Scholar 

  20. Hammarström L, Axelsson U, Björkander J, Hanson LÅ, Möller E, Smith CIE: HLA antigens in selective IgA deficiency: Distribution in healthy donors and patients with recurrent respiratory tract infections. Tissue Antigens 24:35–39, 1984

    Google Scholar 

  21. Björkander J, Hammarström L, Smith CIE, Buckley RH, Cunningham-Rundles C, Hanson LÅ: Immunoglobulin prophylaxis in patients with antibody deficiency syndromes and anti-IgA. J Clin Immunol 1:8–15, 1987

    Google Scholar 

  22. Hammarström L, Grubb R, Oxelius VA, Persson U, Smith CIE, Svejgaard A: Concomitant deficiency of IgG4 and IgE in IgA deficient donors with high titers of anti-IgA.In Immunoglobulin Subclass Deficiencies (Monogr Allergy 20), LÅ Hanson, T Söderström, VA Oxelius (eds). Basel, Karger, 1986, pp 234–235

    Google Scholar 

  23. Björkander J, Oxelius VA, Söderström R, Hanson LÅ: Immunoglobulin treatment of patients with selective IgG subclass and IgA deficiency states (in press)

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Authors and Affiliations

  1. Departments of Clinical Immunology and Pediatrics, University of Göteborg, Göteborg, Sweden

    L. Å Hanson, J. Björkander, B. Carlsson, D. Roberton & T. Söderström

Authors
  1. L. Å Hanson
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  2. J. Björkander
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  3. B. Carlsson
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  4. D. Roberton
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  5. T. Söderström
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Hanson, L.Å., Björkander, J., Carlsson, B. et al. The heterogeneity of IgA deficiency. J Clin Immunol 8, 159–162 (1988). https://doi.org/10.1007/BF00917561

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  • DOI: https://doi.org/10.1007/BF00917561

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