Abstract
A new pharmacokinetic model is proposed to explain the hepatobiliary transport of a nonmetabolized sulfonic acid dye, bromphenol blue, which is actively transported from the bloodstream into bile. This model has the advantage of taking into account the roles of the liver cytoplasmic Y- and Z- binding proteins and T binder.
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Takada, K., Muranishi, S. & Sezaki, H. Pharmacokinetics of the hepatobiliary transport of bromphenol blue as a model of organic anionic compounds. Journal of Pharmacokinetics and Biopharmaceutics 2, 495–509 (1974). https://doi.org/10.1007/BF01070944
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DOI: https://doi.org/10.1007/BF01070944