Summary
The incubation of rabbit heart mitochondria in the presence of ferrous ions induced lipid peroxidation which was accompanied by a reduction of mitochondrial respiratory capacity and Ca+- transport. The effects were more evident, when pyruvate was employed as respiratory substrate, and were partially prevented by catalase, while superoxide dismutase was ineffective.
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Ceconi, C., Curello, S., Albertini, A. et al. Effect of lipid peroxidation on heart mitochondria oxygen consuming and calcium transporting capacities. Mol Cell Biochem 81, 131–135 (1988). https://doi.org/10.1007/BF00219315
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DOI: https://doi.org/10.1007/BF00219315