Abstract
Immunohistochemical changes of heat shock protein 70 (HSP 70) and glial fibrillary acidic protein (GFAP) were investigated in the gerbil hippocampus 1 h-7 days after 10 min of cerebral ischemia. Transient cerebral ischemia caused HSP 70 expression in GFAP-positive astrocytes in a delayed fashion, as compared with a rapid induction in vulnerable neurons such as hilar neurons. The present results may offer clues to elucidate the mechanisms of ischemic neuronal damage.
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Araki, T., Kato, H., Liu, XH. et al. Induction of heat shock protein 70 and glial fibrillary acidic protein in the postischemic gerbil hippocampus. Metab Brain Dis 9, 369–375 (1994). https://doi.org/10.1007/BF02098883
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DOI: https://doi.org/10.1007/BF02098883