Abstract
The effects of dietary soya bean trypsin inhibitor (SBTI) and of the daily injection of pure CCK or porcine intedstinal extract have been studied on the rat pancreas. The following parameters were measured: weight, DNA, RNA, trypsin, chymotrypsin, amylase, lipase, insulin and glucagon. The effects of dietary SBTI on the level of gastrin in the antrum have also been studied. Oral SBTI and i.p. CCK caused similar hypertrophy and hyperplasia but not the same activities of the enzymes. It is suggested that SBTI stimulates the secretion of at least two gastro-intestinal hormones: CCK and gastrin.
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Temler, R.S., Dormond, C.A., Simon, E. et al. The effect of feeding soya bean trypsin inhibitor and repeated injections of cholecystokinin on rat pancreas. Plant Food Hum Nutr 35, 315–321 (1985). https://doi.org/10.1007/BF01092200
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DOI: https://doi.org/10.1007/BF01092200