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Antigenic relationship between Chang liver cells and human hepatocytes

Antigenverwandtschaft zwischen Chang Leberzellen und menschlichen Hepatozyten

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Zusammenfassung

Mit Hilfe monospezifischer Antiseren gegen menschliches lebermembranspezifisches Protein (LSP) konnte gezeigt werden, daß Chang Leberzellen LSP auf der Zellmembran besitzen. Chang Leberzellen können daher als in vitro System zur Untersuchung immunologischer Reaktionen gegen LSP in menschlichen entzündlichen Lebererkrankungen benutzt werden.

Summary

Using monospecific antisera against human liver specific protein (LSP) it could be demonstrated that Chang liver cells bear LSP on their membranes. Chang liver cells can therefore be used as in vitro system to study immune reactions against LSP in human inflammatory liver diseases.

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Hütteroth, T.H., Meyer zum Büschenfelde, K.H. Antigenic relationship between Chang liver cells and human hepatocytes. Klin Wochenschr 56, 525–527 (1978). https://doi.org/10.1007/BF01492866

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