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Target fasting glycaemia for pump-treated type-i diabetics

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Summary

In 17 type-I diabetic patients on continuous s.c. insulin infusion (CSII) therapy, potential interrelationships between fasting levels of blood glucose (BG), serum free insulin (free IRI), total (free and bound) insulin (total IRI) and insulinbinding immunglobulin G (IgGI) were evaluated. There was no consistent relationship between the basal s.c. infused insulin dosages and the associated insulinaemia or glycaemia. A significant inverse correlation was found between the fasting levels of serum free IRI and BG (P<0.005). On the basis of this interrelationship, a target range of 90–110 mg/dl for fasting BG during CSII treatment is proposed.

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Authors and Affiliations

  1. Medizinische Klinik E, Universität Düsseldorf, Germany

    E. A. Chantelau, G. E. Sonnenberg, F. Best & M. Berger

  2. Medical Department, Novo Alle, Novo Research Institute, Bagsvaerd, Denmark

    L. G. Heding

Authors
  1. E. A. Chantelau
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  2. G. E. Sonnenberg
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  3. F. Best
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  4. L. G. Heding
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  5. M. Berger
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Additional information

This study was in part presented at the 18th Annual Meeting of the European Association for the Study of Diabetes (EASD) in Budapest, Hungary, 1–4 September 1982

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Chantelau, E.A., Sonnenberg, G.E., Best, F. et al. Target fasting glycaemia for pump-treated type-i diabetics. Klin Wochenschr 62, 328–330 (1984). https://doi.org/10.1007/BF01716450

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  • DOI: https://doi.org/10.1007/BF01716450

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