Summary
Seventy-one patients (ages: 15–58 years) suffering from complicated migraine were investigated by means of cerebral angiography which was not performed during an attack. Angiography was carried out to exclude stenoses or occlusions of the cranio-cervical vessels and above all vascular malformations (arterial aneurysms, arteriovenous angiomas). In 18 cases (25.4%) organic lesions were found, including three vessel malformations (4.2%). Thirty-one patients (43.7%) suffered from headache reactions or other complications during or within 24 h following angiography. In 15 cases (21.1%) attacks of complicated migraine were observed, three patients (4.2%) suffered from headache and bilateral flickering visual disturbances, another 11 patients (15.5%) developed headache and vegetative symptoms requiring therapeutic management. One patient (1.4%) got an epileptic seizure, another patient (1.4%) developed a generalized urticaria exanthema. There were more headache reactions in women than in men. However, the highest percentage of reactions was observed in patients in whom migraine headache had occurredclearly set off from the transient cerebral functional disturbances. Neurological complications (transient functional disturbances) occurred in 16 of 71 patients (22.5%). The neurological complication rate was significantly (P < 0.001) higher than that in an unselected group of patients (3.0%). However, apart from one case with an acute organic psychosis and permanent amnesia during the angiographic investigation and the postangiographic period, only transient functional disturbances without permanent deficits were seen. In view of the benign course of the complications, it is our opinion that in spite of the high rate of headache reactions angiography should be performed in patients with complicated migraine. Cerebral angiography is the only method of reliably diagnosing intracranial arterial stenoses, occlusions and vascular malformations. Without angiography and thus without diagnosis patients would be considerably endangered (possible rupture of the malformation with fatal consequences).
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Holzner, F., Wessely, P., Zeiler, K. et al. Zerebrale Angiographie bei komplizierter Migraine — Reaktionen, Zwischenfälle. Klin Wochenschr 63, 116–122 (1985). https://doi.org/10.1007/BF01734249
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DOI: https://doi.org/10.1007/BF01734249